Antonio Brown will have a Sunday tilt against the Bills, who have allowed eight touchdowns to opposing wide receivers over their last five games.
Tyler Eifert will take on the Browns in Week 14, who he had 53 yards and three touchdowns against in a single game last season.
Ezekiel Elliott turned 20 rushing attempts and four receptions into 105 total yards and a touchdown against a very stingy Minnesota Vikings defense last Thursday, giving him 10 straight games with at least 97 total yards and a Dallas Cowboys rookie record-tying 13 touchdowns on the season, superlative marks that he will try to build upon this week against a New York Giants that ranks 13th in the NFL in production allowed to opposing running backs.
Dan Bailey made his only field goal attempt and both extra points last Thursday against the Minnesota Vikings and has not missed a field goal since Week 4, a streak that he hopes to build on this week against a New York Giants defense that has allowed an NFL-high 34 field goal attempts this season.
David Johnson turned 18 carries and nine receptions into 175 total yards and two touchdowns on Sunday against the Washington Redskins, and has gone over 100 yards from scrimmage in all 12 games this season plus turned in 15 touchdowns overall, lofty marks headed into this week's game against an average Miami Dolphins defense that ranks 16th in production allowed to opposing running backs.
A Week 13 bye week came at the right time for DeMarco Murray, who is nursing a toe injury as the Tennessee Titans prepare for a Week 14 matchup against the Denver Broncos, who rank 28th in rushing defense.
Donte Moncrief is riding a five-game touchdown streak, the first Colt since Reggie Wayne in 2009 to accomplish such a feat, entering Week 14 against the Houston Texans.
Dez Bryant caught four of six targets for 84 yards and a touchdown last Thursday against Xavier Rhodes and the Minnesota Viking, marking four straight games with at least 72 yards and four touchdowns total over that stretch, and Bryant hopes to build on that success this week against a New York Giants defense that ranks tenth in the NFL in production allowed to opposing wide receivers.
Larry Fitzgerald caught 10 of 11 targets for 78 yards last Sunday in a win over the Washington Redskins, and is tied with Antonio Brown for the league lead with 88 receptions entering this week's game against a Miami Dolphins defense that ranks 17th in the NFL in production allowed to opposing wide receivers.
Jameis Winston has broken the 3,000-yard barrier through a dozen games and faces a Saints defense on Sunday that’s allowed the second most net passing yards this season.
Nick Novak ranks 17th in scoring with 7.2 points per game entering Week 14 against the Indianapolis Colts, who rank 25th in scoring defense.
Julian Edelman has a staggering 40 targets over the last three games, and that trend of heavy involvement should continue on Monday against a Baltimore Ravens defense that's allowing just 222 passing yards per game in 2016.
Adam Vinatieri is tied for eighth with 8.2 points per game and could get on a roll if the Indianapolis Colts' offense repeats its Week 13 performance (41 points) in Week 14 against the Houston Texans.
Marcus Mariota is the hottest quarterback on the planet, but will need more than past performance in Week 14 against the Denver Broncos' top-ranked passing defense.
Andrew Luck (concussion) returned from a one-game absence in style and has the Indianapolis Colts in control of their own destiny heading into Week 14 against the Houston Texans.
Andy Dalton will be up against the Browns in Week 14 after throwing for 308 yards and two touchdowns against them earlier in the season.
Stephen Gostkowski connected on four field goals last week, though Monday Night's tilt with the Baltimore Ravens should be a low-scoring affair, as both squads are allowing just 17.3 points per game in 2016.
Matt Bryant hit a trio of field goals (including a 59-yarder) last week and has once again established himself as a top fantasy kicking option, and he'll look to keep rolling Sunday against the Rams.
Lamar Miller, who is fighting through a rib injury, is experiencing decreased touches-per-game entering Week 14 against the Indianapolis Colts, who rank 20th in rushing defense.
Drew Brees has completed 70 or more percent of his passes in seven-straight games and leads the league in touchdowns and faces a Bucs defense on Sunday that’s allowed 22 passing touchdowns this season.
Matt Ryan had an off-game against the Chiefs, but should get more opportunities on Sunday against the Rams, who allowed Drew Brees to go for five total touchdowns two weeks ago.
Carson Palmer completed 30 of 46 pass attempts for 300 yards and three touchdowns last Sunday against the Washington Redskins, giving him seven touchdowns vs three interceptions in his last three games, marks he hopes to build upon this week against a Miami Dolphins defense that ranks 28th in production allowed to opposing quarterbacks this season.
Jeremy Hill will have a Week 14 tilt against the Browns after lighting them up for 192 yards and a touchdown on 11 touches earlier this season.
Tom Brady has passed for under 300 yards in three-straight games and will face a Baltimore Ravens defense in Week 14 that's allowing just 222 passing yards per contest, which is seventh in the NFL.
Matt Forte has a chance to rebound on Sunday against the league's worst rushing defense of the San Francisco 49ers, a unit that's allowed a staggering 169.3 rushing yards per game in 2016.
Mike Evans had season lows in receptions (3) and yards (38) last week, but the best antidote will be playing the Saints in Week 14, who have allowed the second-most net passing yards this season.
T.Y. Hilton overcame a back injury and is looking healthy heading into an important Week 14 matchup against the Houston Texans.
Amari Cooper again took a back seat to Michaal Crabtree last week, but could rebound Thursday against a Chiefs defense allowing 263.0 passing yards a game, 22nd in the league.
LeSean McCoy has posted back-to-back 100-yard outputs, but faces a Pittsburgh defense in Week 14 that's surrendering just 92 rushing yards per contest, which is sixth in the NFL.
Wil Lutz hit a pair of field goals last week and in the Saints’ typically high octane offense, he should get plenty of chances to score in Sunday’s divisional matchup with the Bucs.
Marqise Lee is the brightest spot in a passing game that has sorely regressed this season as the Jacksonville Jaguars prepare for a Week 14 matchup against the Minnesota Vikings, who rank second in yards allowed per game to wide receivers.
Matt Prater is surging, having gone for double-digit points in three of his last four outings, including seven kicks from 40 yards or more entering a contest against a Bears defense that ranks 16th points allowed at 22.5.
Robby Anderson caught the Jets lone touchdown pass versus the Colts, was targeted a team-high 12 times for the game, and will face a San Francisco 49ers defense in Week 14 that's allowed 26 passing scores in 2016, which is tied for 30th in the NFL.
Michael Crabtree saw double-digit targets last week for the fourth time in six games, and that volume should allow him to remain productive Thursday against a Chiefs defense allowing 263.0 passing yards a game, 22nd in the league.
Taylor Gabriel has 18 receptions for 321 yards and four touchdowns over his past five games and could be in line for even more work on Sunday against the Rams with Julio Jones banged up.
Jordy Nelson has gone for at least 91 yards in five of his last six games, scoring five times, heading into a matchup with the Seahawks ninth-ranked pass defense that allows 231 yards per game, and just 11 touchdown passes in 12 games, the third lowest total.
Cairo Santos failed to get a field goal attempt in Week 13 for the first time all season, but should see more opportunities Thursday against a Raiders defense allowing 24.9 points per game, 22nd in the league.
Cameron Brate could see his role continue to expand against the Saints in Week 14 if Doug Martin and Adam Humphries can’t go after turning in a season-high in yards while pulling in six receptions and a touchdown last week.
Matthew Stafford has led the Lions to seven wins in their last eight games, but has just seven touchdowns in his last six games entering a Week 14 matchup with a sixth ranked Chicago defense that allows 220 passing yards per game.
Sammy Watkins was targeted a team-high nine times this past Sunday, though managed just three catches and is still getting over a foot injury; he'll face a mediocre Pittsburgh passing defense in Week 14 that's allowing 256 passing yards per game, which is 19th in the NFL.
Thielen has 15 catches on 20 targets in his last two games, giving him some appeal despite low yardage upside against a Jaguars second-ranked secondary that allows only 196 yards per game.
Jonathan Stewart has seven touchdowns on the season and faces a Chargers defense in Week 14 that’s allowed 16 rushing touchdowns (the third-worst mark in the league).
Brandin Cooks has five games with seven receptions this season, but has still fallen behind Michael Thomas in the passing game pecking order and faces a Bucs secondary in Week 14 that’s allowed no 100-yard receivers since Week 9.
Cam Newton completed less than 50 percent of his passes for the third-straight game and faces a Chargers defense in Week 14 that leads the league in interceptions.
Tyler Boyd will face the Browns on Sunday after posting at least 54 yards in each of his last three games.
Michael Thomas has at least four receptions and 40 or more yards in every game throughout his career (12 games) giving him the kind of floor most receivers can only dream of, but his upside may be limited Sunday against a Bucs defense that’s allowed just three 100-yard receivers this season.
Coby Fleener has nine receptions for 145 yards over his past two games and faces a Bucs defense on Sunday that’s allowed four or more receptions to tight ends in each of the past four weeks.
Malcolm Mitchell has 17 grabs for 222 yards and three touchdowns over his last three games, though will face a stingy Baltimore passing defense in Week 14 that's allowing just 222 passing yards per game in 2016, which is seventh in the NFL.
Terrelle Pryor will take on the Bengals this Sunday after catching just two passes for 18 yards against them in an earlier meeting this season.