DeAndre Hopkins posted his sixth game of at least 100 receiving yards last week and could repeat that Week 17 against Jacksonville, if the Texans can't get the running game going (3.2 YPA last three games).
T.Y. Hilton dragged his injured ankle up and down the field last week, surpassing 100 yards for the fourth time in Indianapolis' last six games, and he'll need to keep rolling, as Indy looks to clinch a playoff berth in Week 17 against Tennessee.
Julio Jones played through hip and rib injuries last week, but assuming he's out there for the Falcons in Week 17, the star wide receiver will be looking to pad his season totals of 104 catches, 1,539 yards and seven touchdowns against a Buccaneers defense that gives up 251.4 passing yards per game.
Robert Woods has posted between 61 and 89 yards in each of his last nine games, and he'll be a strong fantasy option in Week 17 when the Rams face a 49ers defense that allows the fourth-most fantasy points to opposing WRs.
Mike Evans will be looking for a strong finish to a campaign that's already featured 80 catches for 1,418 yards and six touchdowns when his Buccaneers host the Falcons in Week 17.
JuJu Smith-Schuster caught 11 of his 15 targets for 115 yards, which is the ninth time this season he has totaled over 100 yards, and in Week 17 he'll have a good chance to get his 10th when the Steelers face the Bengals, who give up the fifth-most receiving yards per game.
Davante Adams has double-digit targets in four straight games while scoring in four of five, and should see a healthy portion of looks in Week 17 against Detroit for a receiving corps beleaguered by injury.
Antonio Brown had two straight weeks with less than 50 yards receiving until last week when he had his best performance of the season, catching 14 passes for 185 yards and two touchdowns, and he'll have another chance for a big game in Week 17 when the Steelers face off against the Bengals, who give up the fifth-most receiving yards per game.
Sterling Shepard finally had a big game in the absence of Odell Beckham for the Giants, and with the Dallas Cowboys already locked into their playoff position heading into Week 17, Shepard could be in line for a huge outing despite the Cowboys allowing just 230.5 passing yards per game overall, which is ninth in the NFL.
Jamison Crowder led the Redskins in receiving for the third-straight game and will face an Eagles defense in Week 17 allowing 283 passing yards per game, which is dead last in the NFL.
Taywan Taylor led Tennessee's receivers last week for the third time in four games and is finishing the season on a strong note as he prepares for Week 17 against Indianapolis.
Julian Edelman could find his role expanded with the continued absence of Josh Gordon heading into Week 17 against the Jets, who allowed 442 passing yards to the Packers last week.
Tyreek Hill produced 91 scrimmage yards in Sunday's loss, and with the Chiefs still fighting for playoff seeding, he likely won't be rested in Week 17 against a Raiders defense that's given up a league-worst 34 passing TDs on the season.
Robby Anderson was the Jets leading receiver for the fourth-straight week, reeling in nine passes for 140 yards and a touchdown and could be in line for another big game against the bottom-half Patriots secondary in Week 17.
Kenny Golladay saw 15 of the Lions' 41 targets last Sunday and has at least eight looks in six of the team's last seven outings entering a Week 17 contest against a Packers defense that has allowed eight touchdown passes and two 100-yard receivers in their last three outings.
Keenan Allen caught five of eight targets for 58 yards Saturday, but he should rebound in Week 17 when the Chargers face a Broncos defense he scorched for a 9-89-1 line on 12 targets earlier in the season.
Brandin Cooks hasn't scored a TD or reached 63 yards in any of the Rams' last four contests, but he'll have an excellent Week 17 matchup when the Rams face a 49ers defense that allows the fourth-most fantasy points to opposing WRs.
Cordarelle Patterson ran for 66 yards on four carries as the Patriots relied heavily on the run against the Bills and could look to their converted wide receiver on the ground again versus the Jets in Week 17, who have allowed the seventh-most rushing yards per game this season.
Doug Baldwin has been held to fewer than 40 yards in the majority of his games since the Week 7 bye, and he'll have a tough matchup in Week 17 when Seattle faces an Arizona defense that allows the ninth-fewest fantasy points to opposing WRs.
Curtis Samuel has caught at least four balls in five of Carolina's past seven games, and he'll look to stay involved in the offense in Week 17 against a Saints defense that's allowing 269.3 passing yards per game.
Zay Jones led the way for the Bills with five receptions for 67 yards and a touchdown, but will continue to be plagued by Josh Allen's inaccuracy heading into Week 17 against the Dolphins.
Dontrelle Inman's role increased after Eric Ebron (concussion) left last week's game and scored his second TD since joining Indianapolis, as he prepares for Tennessee's sixth-ranked pass defense in Week 17.
Adam Thielen has five catches in three of the Vikings last four games, going for at least 70 yards in three of their last five, suggesting a stable floor even in the face of a difficult Week 17 matchup against the Bears' eighth-ranked pass defense that allows only 228 yards per game.
Tyler Boyd missed last week's game with a knee injury, plus he is questionable for Week 17 and with Andy Dalton and A.J. Green out for the season, the Bengals could definitely use Boyd's talents against the Steelers, who allow the 13th-most receiving yards per game.
Adam Humphries heads into Tampa Bay's Week 17 home meeting with the Falcons' 24th-ranked pass defense having totaled 51 catches for 530 yards and five touchdowns over the past seven games.
DeAndre Carter had six catches for 61 yards last week, his third significant contribution in Houston's last four weeks, and Demaryius Thomas' season-ending injury puts Carter in line for targets Week 17 against Jacksonville's second-ranked pass defense.
Mohamed Sanu recorded his best game of the season with 110 scrimmage yards and a touchdown last week, giving him momentum heading into Atlanta's Week 17 clash with the NFC South rival Buccaneers.
Alshon Jeffery has at least 75 yards receiving over a touchdown in three-straight games for the Eagles and will face a Washington defense in Week 17 allowing 238 passing yards per contest, which is 14th in the NFL.
Robert Foster strung together another strong game for the Bills as they have established something of a passing game over the past few weeks and will look to close the season out on a high note in Week 17 against the Dolphins.
Stefon Diggs has scored in five of the Vikings last seven games, and while he's seen only 25 targets in his last four outings with the team focusing more on the run, he'll face a Bears defense in Week 17 that he torched for a 13-126-1 line earlier in the year.
Jordy Nelson caught seven of 10 targets for 75 yards Monday, and he should be productive again in Week 17 when the Raiders take on a Chiefs defense that's allowed the most passing yards in the league.
Jarvis Landry didn't just get a team-high eight targets last week, but the Browns got him involved by letting him throw a pass and carry the ball, however in Week 17, he'll be a tough player to trust when he faces a top Ravens defense that gives up third-fewest receiving yards per game.
Courtland Sutton caught six passes for 65 yards and a touchdown on a season-high 10 targets Monday, but he'll have a tougher matchup in Week 17 when the Broncos face a Chargers defense that ranks seventh in passing yards allowed.
Dante Pettis San Francisco's last game with a knee injury and will miss the Week 17 matchup against the Rams.
Jermaine Kearse looked more like a Quincy Enunwa replacement against the Packers, catching four passes for 55 yards and could be in line for another solid game against the Patriots in Week 17.
Marquez Valdes-Scantling could regain a meaningful role for the Packers in Week 17 thanks to a plethora of injuries across their receiving corps against a Lions' secondary that ranks 10th in yards allowed at 231, but 24th in touchdown passes allowed at 29.
Allen Robinson has seen at least even targets in each of the Bears last four games, going for 79 yards or more twice, but hasn't scored in six weeks entering a Week 17 matchup against a Vikings pass defense that hasn't more than 66 yards to an opposing wideout since Week 8.
Nelson Agholor is coming off his first 100-yard game of the season for the Eagles and will face a Washington defense in Week 17 allowing 238 passing yards per contest, which is 14th in the NFL.
Dede Westbrook continues to be the rare light for a below-average Jacksonville offense, and he leads the team in catches, yards and touchdowns entering Week 17 against Houston.
Josh Reynolds is averaging four receptions over the Rams' last four games, but he'll have an upside matchup in Week 17 when the Rams face a 49ers defense that allows the fourth-most fantasy points to opposing WRs.
Calvin Ridley has produced at least 90 yards and a touchdown twice in the past seven games, but he's fallen short of 50 yards in each of the other five, so Atlanta's talented rookie will be a high-risk, high-reward option against Tampa Bay's 22nd-ranked secondary in Week 17.
Isaiah McKenzie saw the second-most targets on the Bills with eight, but reeled in just one catch and will look to close out the season strong in Week 17 against the Dolphins.
Donte Moncrief rebounded from a catch-less Week 15 to nab four passes last week, but Jacksonville's inferior quarterback play will continue to suppress Moncrief in Week 17 against Houston.
Darius Jennings had a season-high three receptions last week, but that was a random occurrence for a WR that didn't have any catches in Tennessee's previous four games and will have a minor role Week 17 against Indianapolis.
Ted Ginn returned from injured reserve to post five catches for 74 yards last week, and he'll likely see at least a few snaps for the Saints in Week 17 against Carolina while many of the team's top weapons rest.
Vyncint Smith popped up on the radar last week, scoring his first NFL touchdown, and will have an increased role with Demaryius Thomas (Achilles) out for Week 17 against Jacksonville's second-ranked pass defense.
John Brown continues to struggle with Lamar Jackson under center for the Ravens, including last week, which was his eighth straight week without 30 or more receiving yards and in Week 17, he'll be tough to start in fantasy, even though the Browns give up the sixth most-receiving yards per game.
Amari Cooper has produced two duds in a row for the Cowboys, gaining just 52 receiving yards in the last two contests; it remains to be seen how much the Dallas starters will play in Week 17 versus the Giants, as the Cowboys are locked into the No. 4 seed in the NFC playoffs.
Tyler Lockett rarely sees more than six targets in a game, and he'll likely need a big play to be a fantasy factor in Week 17 when Seattle plays an Arizona defense that allows the ninth-fewest fantasy points to opposing WRs.
Chris Conley caught three of five targets for 54 yards Sunday, and his workload remains tied to Sammy Watkins' availability heading into the Chiefs' Week 17 clash with a Raiders defense that's given up a league-worst 34 passing TDs on the season.