Mike White has thrown four interceptions and no touchdowns over his last three starts for the Jets, and in Week 18, he'll get a Miami defense that has given up 24.6 points per game in 2022, the sixth-highest total in the league.

Trevor Lawrence is on a two-game passing touchdown drought after throwing 13 touchdowns over the preceding five games, but he can lead the Jaguars to the playoffs with a Week 18 home win over the AFC South rival Titans, who have allowed the most passing yards in the league.

Brock Purdy has thrown two touchdown passes in each of his five games while leading the 49ers offense, and he could continue that trend in a Week 18 matchup against a Cardinals defense that's allowed 1.6 passing TDs per game and the ninth-most fantasy points to opposing QBs.

Justin Fields has topped 70 yards rushing in eight of the Bears last 10 games, but has topped 200 yards passing just once in that stretch, potentially leading to volatility in a Week 18 matchup against a Vikings defense that's being shredded through the air (7.4 ypc, 273.4 ypg) but has allowed 50+ rushing yards to only two quarterbacks to date.

Kirk Cousins has multiple touchdown passes in four of the Vikings last six games, a trend that could prove difficult to repeat in a Week 18 matchup against a getable Bears defense that allows 7.5 ypa, but only 21 touchdown passes in 16 games as teams have found far greater success attacking their bad run defense.

Justin Herbert threw multiple touchdowns last week for the first time since Week 12, but with the Chargers trying to secure the fifth seed in the AFC, he may need to be productive again versus a Broncos defense that held him to 238 yards and zero TDs in their first meeting this season.

Jarrett Stidham dazzled in his first career NFL start last week, but a sore elbow could prevent him from getting a chance to prove it wasn't a fluke in Week 18 as the Raiders take on a Kansas City defense that's given up a league-high 32 passing TDs this season.

Colt McCoy missed the Cardinals' last game with a concussion, casting doubt on his status going into a Week 18 matchup against a 49ers defense that's given up just under 1.2 passing TDs per game and the 12th-fewest fantasy points to opposing QBs.

Geno Smith is averaging 213 passing yards and 1.33 TDs over the Seahawks' last three games, and he could struggle to get back on track in a Week 18 matchup against a Rams defense that's allowed 1.3 TD passes per game and the eighth-fewest fantasy points to opposing QBs.

Desmond Ridder has yet to score a touchdown across his first three starts as Atlanta heads into a Week 18 matchup against a Tampa Bay defense that has been exactly league average in fantasy points allowed to opposing quarterbacks this season.

Jared Goff hasn't thrown an interception since Week 9 and has multiple touchdown passes in five of the Lions last six games, but faces a tough test on the road in Week 18 against a surging Packers secondary that's allowed three touchdowns while snagging seven interceptions over three games since their bye week.

Sam Darnold threw for multiple touchdowns for the first time this season in a Week 17 loss as the Panthers head into a Week 18 matchup against a New Orleans defense that has allowed the eighth-fewest fantasy points per game to opposing quarterbacks in the last four games.

Tyler Huntley has thrown just two passing touchdowns in five starts for the Ravens this year, and if Lamar Jackson still can't go in Week 18, the Utah product will get a Cincinnati defense that has given up 20.4 points per game so far in 2022, the seventh-lowest total in the league.

Taylor Heinicke lost his starting job to Carson Wentz, who tossed three picks last game for Washington, so it remains to be seen who will line up under center in Week 18 versus a Dallas defense allowing just 203.6 passing yards per tilt, which is ninth in the NFL.

Josh Allen has accounted for multiple scores in all but two outings this season for the Bills, and in Week 18, he'll get a New England defense that has allowed 19.5 points per game in 2022, the fifth-lowest total in the league.

Sam Ehlinger threw his first NFL touchdown in relief last week with the game well out of hand, and the Colts' sixth-round selection in the 2021 NFL Draft will make his third start of the season in Week 18 against a Texans defense that's allowed a league-low 13 passing touchdowns this season.

Skylar Thompson has thrown one touchdown to three interceptions in limited duty this year for the Dolphins, but if Teddy Bridgewater can't go in Week 18, the Kansas State product will get the start against a Jets defense giving up 19.1 points per game in 2022, the fourth-lowest total in the league.