Raheem Mostert has scored in three out of four games for the Dolphins this season, and in Week 5, he'll get a Giants defense that has allowed running backs to reach the end zone five times via the ground already in 2023, the third-highest total in the league.

Greg Zuerlein has not missed from under 50 yards for the Jets this season, and in Week 5, he'll get a Broncos defense that has allowed 37.5 points per game so far in 2023, the highest total in the league.

Michael Pittman had just one catch last week after notching at least eight receptions in each of the first three games, but the Colts' No. 1 receiver has a nice opportunity to bounce back in Week 5 against a Tennessee secondary that has allowed the fourth-most catches (71) and fifth-most yards (825) to wide receivers.

James Conner rushed for a season-low 52 yards last game for Arizona but will face a suspect Bengals run defense in Week 5 allowing 157 rushing yards per contest, which is 31st in the NFL.

Riley Patterson has not missed a field goal attempt for the Lions this season after making 85.7% of his attempts in 2022 for Jacksonville, and in Week 5 he faces a Carolina defense that has allowed 25.5 points per game in 2023, which is tied for 24th in the NFL.

Terry McLaurin registered season highs in receptions, targets and receiving yardage last game for Washington and will face a suspect Bears pass defense in Week 5 allowing 267.8 passing yards per tilt in 2023, which is 29th in the NFL.

Davante Adams overcame a minor shoulder injury and a rookie quarterback making his NFL debut last week to still haul in eight catches for 75 yards, and if Jimmy Garoppolo is back under center for the Raiders in Week 5, the superstar wideout figures to be his top target, even in a tough matchup against a Packers secondary that ranks in the top seven in catches and receiving yards allowed to WRs this season.

Travis Etienne has notched exactly 23 touches in three of Jacksonville's first four games, and he should make the most of his opportunities in Week 5 against a Buffalo defense that's been gashed for 6.0 YPC by running backs.

Jason Sanders has made four of his six field-goal tries for the Dolphins this season, and in Week 5, he'll get a Giants defense that has given up 30.5 points per game so far in 2023, the third-highest total in the league.

Garrett Wilson has yet to top 83 yards in an outing this season for the Jets, but in Week 5, he'll get a Broncos defense that has allowed 35.9 fantasy points per game to wide receivers so far in 2023, the seventh-highest total in the league.

Derrick Henry had at least 100 yards and a touchdown in the same game seven times last season, and the star Tennessee RB is coming off his first such game of 2023 ahead of a Week 5 road matchup with a Colts defense that's allowing 126.8 rushing yards per game.

DJ Moore has topped 100 receiving yards in two of the Bears' last three contests, and he faces a Commanders defense in Week 5 that has allowed six touchdowns to opposing wide receivers this year, tied for most in the NFL.

Sam Howell rebounded with 290 passing yards and a touchdown last game for Washington and will face a suspect Bears defense in Week 5 in the bottom five of the NFL in terms of passing yards allowed and passing touchdowns surrendered in 2023.

Harrison Butker has yet to miss a kick this season, and he figures to see plenty of opportunities in Week 5 as Kansas City faces a Vikings team that's giving up 23.8 points per game, ranking in the bottom half of the league.

Dalvin Cook is averaging 2.5 yards per carry so far this season for the Jets, but in Week 5, he gets a Broncos defense that has allowed 40.5 fantasy points per game to running backs in 2023, the highest total in the league.

Josh Jacobs topped 100 scrimmage yards and scored a rushing touchdown last week for the first time this season, and he could be headed for another big performance in Week 5 as the Raiders face a Packers defense that's allowing 155.3 rushing yards per game, 30th in the league.

Nick Folk has made all 10 of his field-goal attempts for the Titans, and the veteran kicker will look to stay perfect in Week 5 against a Colts team that's giving up 24.8 PPG.

Matthew Stafford is tending to a hip injury but should suit up in Week 5 for the Rams versus an Eagles defense allowing 260.8 passing yards per contest, which is 27th in the NFL.

Ryan Tannehill's averaging just 197 passing yards per game and has a 2:4 TD:INT while managing Tennessee's run-heavy offense, but the veteran QB could be asked to shoulder a larger load in Week 5 against a vulnerable Colts secondary that's allowing the fifth-most passing yards.

T.J. Hockenson saw a season-low three targets last week for the Vikings after fetching eight-plus targets in each of the first three games this season, and he faces a Chiefs defense in Week 5 that has allowed 22 receptions to opposing tight ends so far in 2023, tied for the fifth-highest total in the NFL.

Eddy Pineiro has made multiple field goals in each of his last three games as the Panthers head into a Week 5 matchup against the Lions.

D'Andre Swift has either 100 rushing yards or a touchdown, or both, in each of the last three games for the Eagles and will face a Rams squad in Week 5 allowing 111 rushing yards per outing, which is 14th in the NFL.

Chris Olave was harmed by the Saints' poor passing game in Week 4 against Tampa Bay and will head into a Week 5 matchup against a New England defense that has allowed a league-average 28.3 fantasy points per game to opposing wide receivers this season.

Ka'imi Fairbairn has attempted three field goals in each of Houston's first four games heading into a Week 5 road tilt against a Falcons team that's allowing 19.3 PPG -- 10th-fewest in the NFL.