Jesse James will have a Week 17 tilt against the Browns, who have allowed four touchdowns to opposing tight ends over the last three weeks.
Greg Olsen has 16 receptions over his past three games, and will look to replicate his nine catch, 181 yard performance from Week 5 against the Bucs on Sunday.
Jimmy Graham is primed for another big game Sunday against a 2-13 49ers team that he burned for 100 yards and a touchdown back in Week 3.
Delanie Walker will have to adjust to a new quarterback in Week 17 as Matt Cassel replaces the injured Marcus Mariota (fibula) against the Houston Texans, who rank third in yards allowed per game to tight ends (35.4 ypg).
Charles Clay has scored in three-straight games, and faces a suspect New York Jets passing defense on Sunday that's allowed 30 passing scores in 2016, which is tied for 30th in the NFL.
Zach Ertz has over 300 yards in his past four games combined, and should be able to stay on that pace Sunday against the 28th-ranked Cowboys pass defense.
Travis Kelce hauled in a career-high 160 yards last week, his fifth 100-yard performance in the last six games, and he should be Alex Smith's primary option once again Sunday as the Chiefs look to keep their chances of an AFC West title alive.
Kyle Rudolph has at least eight targets in five straight games, but has topped 65 yards and scored just once in that span, giving him a safe floor with limited upside against a Bears defense that has allowed one tight end to top 50 yards since Week 10, and just two all season.
Coby Fleener had his biggest game of the season in the first meeting with the Falcons (seven receptions, 109 yards and a touchdown), but has just five receptions for 49 yards over his past three.
Martellus Bennett has found the end zone in two of the last three games, and faces a Miami defense on Sunday that's allowed 27 passing scores in 2016, which is tied for 25th in the NFL.
Vernon Davis is no Jordan Reed, but the veteran tight end should be able to find some success filling in for his injured counterpart Sunday against the 22nd-ranked Giants secondary.
C.J. Fiedorowicz returned to action after missing one game due to a concussion and will be ready to roll in Week 17 against the Tennessee Titans, who rank 12th in yards allowed per game to tight ends (52.2 ypg).
Eric Ebron is coming off of a season-high 93 yards and has at least four catches in four straight games heading into a matchup against the Packers 29th ranked pass defense.
Jack Doyle had some noteworthy games during the first half of the season, but hasn't scored a touchdown in eight straight games entering Week 17 against the Jacksonville Jaguars.
Dennis Pitta will have a Sunday matchup with the Bengals, who have allowed four opposing tight end to post at least 42 receiving yards against them over their last four games.
C. J. Uzomah will take on the Ravens in Week 17, as he’s expected to take over the starting role for Tyler Eifert, who is expected to be inactive for the contest.
Garrett Celek is the top healthy tight end left in San Francisco, but that role alone won't net him much value Sunday against the eighth-ranked Seahawks pass defense.
Will Tye has just 348 yards and a touchdown through 15 games, so don't expect much output from the tight end Sunday despite a plus matchup in Washington.
Antonio Gates is now just one touchdown shy of tying Tony Gonzalez's career record for tight ends, but gets a tough matchup Sunday against a Chiefs defense that's given up only two TDs to tight ends all season.
Jared Cook continues to share reps and targets with Richard Rodgers, giving him only a puncher's chance at exploiting a Lions defense that has allowed opposing tight ends to score 10 times this season.
Clive Walford caught his third TD of the season last week, and could be more involved in the Raiders' attack Sunday facing a Broncos defense that just got exposed by Travis Kelce and the Chiefs' tight ends.
Gary Barnidge will have a Sunday tilt against the Steelers, a team he scored his only touchdown of 2016 against when he faced them earlier this season.
Ryan Griffin is back to second string with C.J. Fiedorowicz healthy in advance of Week 17's game against the Tennessee Titans.
Austin Hooper is hopeful to get back on the field in Week 17 against the Saints, who held the Bucs trio of tight ends to just three receptions last week.
Jason Witten scored his third touchdown of the season last week, but he's unlikely to add to that total Sunday against the Eagles with the Cowboys likely to rest their key contributors for most of Week 17.
Erik Swoope has had some notable moments late in the season, but as the third tight end, he remains a risky play in Week 17 against the Jacksonville Jaguars.
Lance Kendricks has topped 40 yards just once in his past seven games heading into Sunday's season finale against the fifth-ranked Cardinals pass defense.
After posting just four catches and 44 yards over the past three games, Dwayne Allen's three-TD outburst in Week 13 is now a distant memory entering Week 17 against the Jacksonville Jaguars.
Daniel Brown has been held under 20 yards in three of his last four outings and has a season-high of 42 yards entering Sunday's matchup with a Vikings defense that hasn't allowed a tight end to top 50 yards since Week 10.
Richard Rodgers caught his first touchdown since Week 3 last week, but continues to split chances with Jared Cook heading into a contest with Detroit, who have only allowed one tight end to score since their Week 10 bye.
Jeff Heuerman saw a career-high six targets last week, and could continue to see steady volume Sunday with Virgil Green and A.J. Derby both dealing with concussions.
Ben Koyack has filled in as the Jacksonville Jaguars' starting tight end with both Julius Thomas (back) and Marcedes Lewis (ankle) done for the season, but will not be a big part of the attack in Week 17 against the Indianapolis Colts.
Jordan Reed is unlikely to suit up Sunday against the Giants after missing Week 16 with a shoulder injury.
Jermaine Gresham is expected to do much more blocking than receiving Sunday in Los Angeles.