Ezekiel Elliott turned 20 rushing attempts and four receptions into 105 total yards and a touchdown against a very stingy Minnesota Vikings defense last Thursday, giving him 10 straight games with at least 97 total yards and a Dallas Cowboys rookie record-tying 13 touchdowns on the season, superlative marks that he will try to build upon this week against a New York Giants that ranks 13th in the NFL in production allowed to opposing running backs.
David Johnson turned 18 carries and nine receptions into 175 total yards and two touchdowns on Sunday against the Washington Redskins, and has gone over 100 yards from scrimmage in all 12 games this season plus turned in 15 touchdowns overall, lofty marks headed into this week's game against an average Miami Dolphins defense that ranks 16th in production allowed to opposing running backs.
A Week 13 bye week came at the right time for DeMarco Murray, who is nursing a toe injury as the Tennessee Titans prepare for a Week 14 matchup against the Denver Broncos, who rank 28th in rushing defense.
Jeremy Hill will have a Week 14 tilt against the Browns after lighting them up for 192 yards and a touchdown on 11 touches earlier this season.
Thomas Rawls carried 15 times for 106 yards and a pair of touchdowns and added a 12-yard reception last Sunday against the Carolina Panthers, by far his best game of the season, and hopes to build upon that this week against a Green Bay Packers run defense that ranks 12th in production allowed to opposing running backs.
Matt Forte has a chance to rebound on Sunday against the league's worst rushing defense of the San Francisco 49ers, a unit that's allowed a staggering 169.3 rushing yards per game in 2016.
Lamar Miller, who is fighting through a rib injury, is experiencing decreased touches-per-game entering Week 14 against the Indianapolis Colts, who rank 20th in rushing defense.
Ryan Mathews missed the last two games due to an injured knee, but he is expected to play this Sunday against a weak Washington Redskins run defense that ranks 29th in the NFL in production allowed to opposing running backs.
Carlos Hyde rushed 20 times for 92 yards and caught a pass for another six yards last week against the Chicago Bears, making three straight weeks that Hyde produced at least 95 total yards, a streak he hopes to continue this Sunday against a New York Jets run defense that ranks 14th in production allowed to opposing running backs.
Theo Riddick is coming off of a season low in touches and yards and now faces a Bears defense that is allowing 3.9 yards per carry and defended him well in Week 4, allowing him to gain 58 total yards
LeSean McCoy has posted back-to-back 100-yard outputs, but faces a Pittsburgh defense in Week 14 that's surrendering just 92 rushing yards per contest, which is sixth in the NFL.
Rob Kelley rushed 14 times for 63 yards last Sunday against the Arizona Cardinals, his second straight down game after three straight big efforts when he first entered the starting line-up, and he will look to bounce back this week against a Philadelphia Eagles defense that is tied for seventh in production allowed to opposing running backs.
Frank Gore could be the weapon of choice in Week 14 against the Houston Texans, who have been stingy against the pass (fifth, 208.4 ypg), but less against the run (19th, 107.7 ypg).
Todd Gurley rushed 11 times and added two receptions for a total of 47 yards last Sunday against the New England Patriots, his lowest yardage total since Week 1, but will look to bounce back this week against an Atlanta Falcons defense that ranks 30th in the NFL in production allowed to opposing running backs.
Melvin Gordon topped 100 yards from scrimmage for the fifth time in the last six games in Week 13, but gets a tough matchup Sunday against a Panthers defense allowing 92.8 rushing yards a game, eighth in the league.
Mark Ingram has 5.3 yards per carry on the season and faces a Bucs defense in Week 14 that’s allowed the seventh-most yards per carry this season.
Spencer Ware scored twice last week despite barely topping 50 yards from scrimmage, and should remain productive Thursday against a Raiders defense allowing 124.8 rushing yards a game, 29th in the league.
Devonta Freeman scored a pair of goal line touchdowns last week and faces the Rams run defense on Sunday that’s in the top-dozen in terms of rushing touchdowns allowed at eight.
Isaiah Crowell will be up against the Bengals in Week 14, after they’ve held every running back they’ve faced over the last five weeks to 87 yards or fewer.
Jonathan Stewart has seven touchdowns on the season and faces a Chargers defense in Week 14 that’s allowed 16 rushing touchdowns (the third-worst mark in the league).
Latavius Murray topped 100 yards from scrimmage last week for just the third time this season, and has another great matchup Thursday against a Chiefs defense allowing 121.9 rushing yards a game, 27th in the league.
Le’Veon Bell will take on the Bills this Sunday, as he’ll try to become the first running back to post over 82 rushing yards against them in six weeks.
Kenneth Dixon will have a Week 14 matchup against the Patriots after posting at least 77 total yards in three of his last four games, though he’s yet to find the end zone in his rookie campaign.
Doug Martin’s health is a question mark going into Week 14 against the Saints, but even if he can play, he’s averaging fewer than 3.0 yards per carry in three of his past four games.
Derrick Henry has fresh legs while DeMarco Murray deals with a toe injury and a heavy workload entering 14 against the Denver Broncos, who rank 28th in rushing defense.
The Jacksonville Jaguars' top three running backs are dealing with injuries, but Yeldon was able to play through his last week, making him the best of a bad lot entering Week 14 against the Minnesota Vikings.
Mike Gillislee swiped two touchdowns from teammate LeSean McCoy last weekend, and faces a Pittsburgh defense in Week 14 that's yielded 10 rushing scores in 2016, which is tied for 19th in the NFL.
Ty Montgomery resurfaced to lead the Packers in rushing last week, and his dual position eligibility give him a shot at relevance against a tough Seahawks defense that is allowing only 99.3 yards per game rushing.
Chris Ivory missed last week's game due to a hamstring injury and is questionable entering Week 14 against the Minnesota Vikings, who rank 17th in rushing defense.
Paul Perkins had seven carries for 38 yards to lead the New York Giants in rushing last Sunday, though he still played a lesser role in the offense than starter Rashad Jennings due to the latter's receiving and blocking abilities, making Perkins a risky play against a tough Dallas Cowboys defense that is fourth in the NFL in production allowed to opposing running backs.
Rex Burkhead will take on the Browns this Sunday after posting at least 48 yards in each of his last two games since taking over for Giovani Bernard.
Devontae Booker hasn't topped a 4.0 YPC since Week 7, and gets another tough matchup Sunday against a Titans defense allowing 92.3 rushing yards a game, seventh in the league.
Dion Lewis continues to split opportunities with James White as the receiving backs in the New England offense, though Lewis appears to be trending towards more touches as he enters Week 14 against the Ravens.
Jordan Howard's steady workload will keep him from bottoming out, but he faces an uphill battle for production against a Lions defense that has allowed over 50 yards to an opposing running back once since Week 7.
Bilal Powell touched the ball just once on Monday Night Football, but has a chance to rebound on Sunday against the league's worst rushing defense of the San Francisco 49ers, a unit that's allowed a staggering 169.3 rushing yards per game in 2016.
Tevin Coleman saw his role expand to 12 carries against the Chiefs, turning it into 49 yards, but ceded the red zone work to Devonta Freeman, which significantly depresses his value on Sunday against the Rams’ middling run defense.
Duke Johnson will have a Week 14 tilt against the Bengals, though he hasn’t had more than eight touches in any of his last five games.
Terrance West will be up against the Patriots on Monday after he’s posted at least 64 total yards in three of his last four games.
LeGarrette Blount ended a two-game scoring drought this past Sunday, but faces the top rushing defense on Monday Night Football, as the Baltimore Ravens are first in the NFL in both rushing yards and rushing touchdowns allowed per contest.
Playing from behind, the Saints ran the ball a total of 12 times last week and their willingness to abandon the run game bodes poorly for Tim Hightower on Sunday against the Bucs, who have allowed just one 100-yard rusher this season.
Jerick McKinnon scored and averaged 4.6 yards per carry last week, two things he hadn't done since Week 4 against the Giants, giving him a but of momentum entering Sunday's matchup with the Jaguars 24th ranked rush defense that allows 115.6 yards per game.
Rashad Jennings had six carries and six receptions for 53 total yards and a touchdown last Sunday against the Pittsburgh Steelers, though rookie Paul Perkins was the more effective ball carrier with seven carries for 38 yards, so Jennings will try to re-assert himself this week against a tough Dallas Cowboys defense that is fourth in the NFL in production allowed to opposing running backs.
Matt Asiata saw a three-game scoring streak snapped last week and has six or fewer carries in three straight games giving him minimal upside against a Jaguars 24th ranked rush defense that allows 115.6 yards per game.
Wendell Smallwood was held to 19 yards on eight carries and three unsuccessful targets last Sunday against the Cincinnati Bengals, and with Ryan Mathews expected to return this week Smallwood is facing a return to a pure back-up role against the Washington Redskins.
James White continues to split the receiving back role with Dion Lewis as he enters Week 14 against the Ravens, though the latter received more touches in last Sunday's game.
Jonathan Grimes, along with Alfred Blue, will get some touches each week, but he's no threat to Lamar Miller's top spot in the backfield entering Week 14 against the Minnesota Vikings.
Corey Grant is a little used on offense, but has the distinction of being the healthiest running back on the Jacksonville Jaguars' roster entering Week 14 against the Minnesota Vikings' 17th-ranked rushing defense.
Jalen Richard saw a season-high nine carries last week, but with Latavius Murray healthy he won't see enough touches to be reliable Thursday, even in a favorable matchup against a soft Chiefs run defense.
Christine Michael saw an expanded role in his second week with the Packers last Sunday, but will continue to split carries with at least Ty Montgomery entering a matchup with his former team in the Seahawks, who allow only 99.3 yards per game on the ground.
Alfred Blue returned to action last week after missing two games with a calf injury, but needs a significant injury to Lamar Miller to have any value in Week 14 against the Indianapolis Colts, who rank 20th in run defense.