Keenan Allen has been productive through two games thanks to a whopping 20 targets, and he should see a high volume again Sunday at home against a Chiefs defense allowing 300 passing yards a game so far.
Antonio Brown caught five of his 11 targets for 62 yards last week against the Minnesota Vikings, lacking big plays but still maintaining the same huge target footprint, which should lead to a major chance to pop this Sunday against a Chicago Bears defense that was just torched by Mike Evans.
Davante Adams could serve as the team's top wide receiver as Jordy Nelson deals with a quad injury, which would make him a high-volume option against a limited Bengals secondary that could be without Adam Jones due to an arm injury.
Chris Hogan will get plenty of opportunities thanks to a injury-plagued receiving corps, even against a Texans defense that is allowing only 169 passing yards per game thus far.
Devin Funchess looks best-poised to step in the void left behind by Greg Olsen (broken foot) as they take on the Saints’ secondary on Sunday that allowed 447 yards to Tom Brady last week.
Kelvin Benjamin rekindled the spark between him and Cam Newton as he played the role of Greg Olsen as primary safety blanket with aplomb and faces a Saints secondary in Week 3 that allowed Tom Brady to throw for 447 yards last week.
A.J. Green caught five passes for 67 yards in Week 2, another mildly productive game that ended without triple-digit yardage or a score, but he will look to bounce back Sunday against a Green Bay Packers secondary that gave up 108 yards to Julio Jones in Week 2.
Jarvis Landry had a staggering 13 receptions in the season opener for the Miami Dolphins, and will face a New York Jets defense allowing 8.1 yards per passing attempt thus far in 2017, which is 25th in the NFL.
DeVante Parker was the leading receiver for the Miami Dolphins in their season opener, and is a great bet to explode against a suspect New York Jets defense which has allowed five passing touchdowns through two contests.
Golden Tate should see plenty of looks against a beatable Falcons secondary in a game that figures to be high scoring, helping offset his current 9.4 yards per catch through two weeks.
Martavis Bryant caught three of four targets for 91 yards and a touchdown last week against the Minnesota Vikings, a huge step up from his quiet opener and a sign that he is at full speed again going into this Sunday's matchup with a Chicago Bears defense that just got torched by the Tampa Bay Buccaneers passing game.
DeAndre Hopkins likely will see another week of double-digit targets Sunday against the Patriots as injuries at wide receiver and tight end have thinned the Texans' receiving corps significantly.
Julio Jones had his first 100-yard game of the season, but faces a Lions secondary on Sunday that held a hobbled Odell Beckham Jr. to four receptions for 36 yards.
Marvin Jones has scored in consecutive games despite only seven combined targets, making him a boom-or-bust option in what figures to be a high-scoring contest against the Falcons in Week 3.
Randall Cobb would see a bump in opportunities if Jordy Nelson (quad) misses Sunday's contest, but Cobb remains a shorter-yardage option and is dealing with his own shoulder injury in advance of a visit from the Bengals.
Brandin Cooks has been a bit of a disappointment thus far in 2017, though if the injuries continue to pile up for the other New England pass catchers, quarterback Tom Brady will have no choice but to look Cooks' way early and often against the Houston Texans.
Terrelle Pryor will be up against the Raiders on Sunday who gave up a pair of receiving touchdowns two Jermaine Kearse of the Jets last week.
Jermaine Kearse has emerged at the No. 1 receiving option for the Jets after two touchdowns last Sunday, and could be a sneaky play against a Miami defense that was gutted for 323 passing yards in Week 2.
Mohamed Sanu caught five passes for 85 yards and has already seen 15 targets this season as he’s firmly ensconced as the Falcons’ No. 2 option in the passing game, and he'll look to extend his success in Week 3 against the Lions.
With more weapons in the passing game, Rishard Matthews is fighting for targets and yards, but he's the Titans' top target entering Week 3 against the Seattle Seahawks.
Kenny Stills continues to show a nose for the end zone no matter who lines up under center for the Miami Dolphins, and he could find the promised land again versus a New York Jets that's already allowed five passing scores in 2017.
Jaron Brown saw a team-leading 11 targets last week, and should be heavily involved again Monday against Dallas, especially if John Brown (quad) sits.
Emmanuel Sanders found the end zone twice against the Cowboys, and his target volume gives him a solid production floor heading into a road matchup Sunday against a Bills defense that's allowed a stingy 68.7 QB rating so far.
Odell Beckham will have a Sunday tilt against the Eagles, who have held the wide receivers they've faced to 66 yards or fewer in each of their first two games on the year.
Doug Baldwin still hasn't scored a touchdown after totaling 21 over the past two seasons, but could turn things around Sunday against a subpar Titans pass defense.
Adam Thielen provided Case Keenum with a safety valve in Week 2, but will need Sam Bradford healthy if he's to provide a solid return in Week 3 against Tampa Bay.
Marqise Lee might not repeat the team-high 12 targets he had last week, but he will continue to be the No. 1 receiver for Jacksonville as the Jaguars face the Ravens in London on Sunday.
Allen Hurns could be reliant on garbage-time production again this week if the Jaguars fall behind early against the Ravens in London, as Jacksonville is certain to see eight-man boxes against the running game.
Pierre Garcon is the only San Francisco wide receiver on the fantasy radar for Thursday's clash with the Rams, as he's turned 15 targets into 107 yards through two weeks.
J.J. Nelson will look to find pay dirt for the third consecutive week against Dallas on Monday Night Football.
Michael Crabtree exploded for three TDs against the Jets, and while he won't match that feat he should remain productive Sunday on the road against a Washington defense allowing almost 280 passing yards a game so far.
DeSean Jackson’s ability to stretch defenses could be the key to unlock the Vikings’ tough secondary in Week 3 as Martavis Bryant, playing a similar role to Jackson, caught a 51-yard pass and drew another 50-plus yard pass interference penalty last week.
Tyreek Hill is coming off a quiet performance against the Eagles, but he remains a threat to bust out a big play or two Sunday even against a Chargers defense that's allowing under 225 passing yards a game so far.
Larry Fitzgerald is a middling standard-league option in Week 3 against a Cowboys defense that's held opponents to 200 passing yards per game, but his volume makes the veteran wide receiver a strong PPR play.
Cooper Kupp has been Los Angeles' best wide receiver through two weeks, but the whole passing game is likely to take a back seat to Todd Gurley and the rushing attack Thursday in San Francisco.
Geronimo Allison would be in line for additional work should Jordy Nelson and/or Randall Cobb sit in Week 3 against Cincinnati due to injuries.
Stefon Diggs needs a healthy Sam Bradford to stretch the Buccaneers defense vertically Sunday, as Case Keenum averaged only 4.51 yards per attempt in last week's start.
Tyrell Williams saw only four targets last week but caught them all, and he could be poised for a rebound Sunday at home against a Chiefs defense allowing 300 passing yards a game so far.
Demaryius Thomas has seen eight targets in two straight games to begin 2017, and should remain a high-priority target for Trevor Siemian in Sunday's road tilt against a Bills defense that's allowed a stingy 68.7 QB rating so far.
Jamison Crowder will have a Sunday tilt against the Raiders, who have held opposing passing attacks to just 211 yards per game.
Amari Cooper wasn't needed in Week 2's dismantling of the Jets, but he should be much more involved Sunday on the road against a Washington defense allowing almost 280 passing yards a game so far.
Rashard Higgins came off the practice squad to lead the Cleveland Browns with seven receptions and 95 yards in Week 2, and could be in for more opportunities in Week 3 if Corey Coleman's hand injury keeps him out.
Terrence Williams has 12 targets through two weeks, but is averaging a mere 8.5 yards per catch entering a Monday night matchup against Arizona.
Markus Wheaton is expected to make his season debut after missing two weeks due to a finger injury, but joins an underwhelming cast of receivers for Mike Glennon and his 6.05 yards per attempt.
Cole Beasley will be up against the Cardinals in Week 3 who gave up 107 yards to Golden Tate, who does much of his work from the slot, in the season opener.
Taylor Gabriel caught just two passes against the Packers and with the Falcons commitment to balance, could find targets hard to come by against the Lions on Sunday.
Golladay lost some targets to tight end Eric Ebron in Week 2, but should be afforded more opportunities against Atlanta on Sunday when the Lions figure to be a bit more pass-happy.
Donte Moncrief, who caught two of eight targets in Week 2, might eventually get on the same page with quarterback Jacoby Brissett, but it might not happen Sunday against the Browns, who rank 12th in yards allowed to wide receivers.
Robby Anderson has taken a backseat to Jermaine Kearse, though he has still been targeted 12 times in two games, and faces a Miami defense that allowed 323 passing yards in Week 2.
Sterling Shepard will be left to fight for touches with other teammates behind Odell Beckham, which makes him a risky fantasy option in Week 3 against the Eagles.