Ben Roethlisberger will have a Week 17 tilt against the Browns, though it’s possible that the team will choose to rest him in a meaningless game.
Eli Rogers will face the Browns in Week 17, after averaging 79.5 yards along with one touchdown over his last two contests.
Adam Thielen has at least 86 yards in three of his last four games and has emerged as the Vikings top receiving threat entering a Week 17 finale against a Bears secondary that has allowed three receivers to top 93 yards in the last two games.
Robbie Gould is likely to stay busy with New York's pass-oriented attack clashing with the league's 25th-ranked pass defense Sunday.
Caleb Sturgis could be called upon more than expected Sunday against a Cowboys team that could choose to rest some starters after clinching the top seed in the NFC.
Alex Collins will serve as the primary running back against the league-worst 49ers run defense Sunday if Thomas Rawls (shoulder) can't suit up, but Rawls is expected to play.
Robert Turbin is tied for second on the Indianapolis Colts with seven touchdowns (six rushing, one receiving) and has scored four times in the last four games entering Week 17 against the Jacksonville Jaguars, who rank 23rd in rushing touchdowns allowed.
Injuries to T.J. Yeldon (ankle) and Chris Ivory (hamstring) make Grant a possible lead back for Week 17 against the Indianapolis Colts, who rank 23rd in rushing defense (116.3 ypg).
Kai Forbath has at least two field goals in every game since Thanksgiving and should have some opportunities in Week 17 against a Bears defense that has allowed 71 points over the past two weeks.
Sam Bradford quietly has 290 yards or more in three straight games, and while his scoring upside is limited against a Bears defense that has allowed only two touchdown passes in the last four weeks, Bradford's floor seems safer than many other quarterbacks in Week 17 who could share snaps in games that matter little to the playoff picture.
Rex Burkhead will take on the Ravens this Sunday, and he could be in for an expanded role if Jeremy Hill is limited or inactive due to the knee injury he battled through last week.
Jamison Crowder closes out the regular season Sunday against the 22nd-ranked Giants secondary.
Kenneth Dixon will have a Week 17 matchup against the Bengals, who he posted 80 total yards against in Week 13.
Matt Moore has six touchdown passes in two starts, but faces a New England defense on Sunday that's allowed just 19 passing scores in 2016, which is tied for seventh in the NFL.
J.J. Nelson takes a four-game scoring streak into Sunday's season finale against the ninth-ranked Rams pass defense.
Alfred Blue is in line to be the Houston Texans' lead back if they decide to limit Lamar Miller (ankle) for a second straight game in Week 17 against the Tennessee Titans' fifth-ranked rushing defense (91.1 ypg).
Ted Ginn has 50 receptions for just the second time in his ten-year career, and faces a Bucs secondary on Sunday that’s allowed the tenth-most receiving yards in the league.
Kenny Stills has found the end zone in three-straight games, but will face a New England defense in Week 17 that's yielded 19 passing scores in 2016, which is tied for seventh in the NFL.
Tyler Boyd will face the Ravens on Sunday after catching five passes for 62 yards in his last meeting against them.
Roberto Aguayo knocked in his only field goal attempt and has gone 14-for-16 on field goals in November and December after missing five of his first 12 attempts, and will look to end the year on a high note this Sunday against the Panthers.
John Brown managed a season-high 10 catches for 144 yards against the Rams in Week 4, but Arizona's No. 3 wide receiver is unlikely to replicate that success in Sunday's rematch.
Byron Marshall will get most of the rushing workload Sunday against the top-ranked Dallas run defense with Ryan Mathews out due to a herniated disc.
Cody Parkey will take on the Steelers in Week 17 after making exactly two field goals in three of his last four games.
Trevor Siemian threw for 283 yards and two TDs in Week 9's meeting with the Raiders, but with the Broncos eliminated from the playoffs and in talent evaluation mode, he could give way to Paxton Lynch at some point in Week 17.
Josh Lambo missed two of his three field goal attempts last week and hasn't kicked multiple field goals in a game since Week 9, making him a risky play Sunday against a Chiefs defense that ranks fifth in scoring defense.
Robert Woods has fallen down the depth chart in terms of targets, though he could find some extra room in Week 17 against a soft Jets passing defense that's allowed 30 passing touchdowns in 2016.
C. J. Uzomah will take on the Ravens in Week 17, as he’s expected to take over the starting role for Tyler Eifert, who is expected to be inactive for the contest.
Andy Dalton will face the Ravens in Week 17, but he’s expected to be without AJ Green and Tyler Eifert in what will be a meaningless season finale for the Bengals.
With Allen Hurns dealing with a hamstring injury and missing the previous three games, Bryan Walters could be the Jacksonville Jaguars' third wideout in Week 17 against the Indianapolis Colts.
Tom Savage will make his second career NFL start in Week 17 against the Tennessee Titans, who rank 31st in passing defense (270.9 ypg).
Jack Doyle had some noteworthy games during the first half of the season, but hasn't scored a touchdown in eight straight games entering Week 17 against the Jacksonville Jaguars.
Charcandrick West saw double-digit touches last week for the first time since Week 9 due to Spencer Ware's rib injury, and could see a similar workload Sunday as the Chiefs look to keep their chances of an AFC West title alive.
Ronnie Hillman could get the start Sunday with Kenneth Farrow (shoulder) on IR and Melvin Gordon (knee) questionable, giving him some upside against a Chiefs defense that ranks 26th in rushing yards allowed per game.
Jason Myers leads the NFL with 11 field-goal attempts from 50 yards or greater and ranks 19th in scoring with 6.8 points-per-game entering Week 17 against the Indianapolis Colts' 24th-ranked scoring defense (24.8 ppg).
Robert Griffin will take on the Steelers in Week 17, but it’s unclear whether or not he’ll start over Cody Kessler after Griffin was forced from last week’s victory with a concussion.
Jermaine Kearse might get a few more targets in the wake of Tyler Lockett's broken leg, but he'll still be a lower-tier option Sunday in San Francisco.
Malcolm Mitchell has just four catches for 43 yards over his last two games, and faces a Miami defense on Sunday that's allowing 240 passing yards per game, which is 13th in the league.
Anquan Boldin has only 46 total yards over the last two weeks, but faces a Packers defense he scored against in Week 3 and one that has allowed 30 touchdown receptions this season, the second-highest total in the league.
Alfred Morris will see more carries than usual Sunday in Philadelphia with Ezekiel Elliott likely to spend msot of the game resting in preparation for the playoffs.
Randy Bullock will be up against the Ravens in Week 17, a defense that’s allowed one or fewer field goals in three of their last four games.
Matt Cassel draws the start for the final game of the regular season with Marcus Mariota (fibula) unable to play Week 17 against the Houston Texans' second-ranked passing defense (206.2 ypg).
Marvin Jones has one catch in three of his last six games and has shown no signs of reclaiming his early season success entering an otherwise exploitable matchup with Green Bay's 29th ranked pass defense.
Tony Romo hasn't played all season, but would get the reps under center should the 13-2 Cowboys choose to rest rookie starter Dak Prescott for Sunday's season finale in Philadelphia.
Adam Humphries caught a single pass last week, but could return to the game plan on Sunday against the Panthers if Cameron Brate is unable to play with his back injury.
Clive Walford caught his third TD of the season last week, and could be more involved in the Raiders' attack Sunday facing a Broncos defense that just got exposed by Travis Kelce and the Chiefs' tight ends.
Garrett Celek is the top healthy tight end left in San Francisco, but that role alone won't net him much value Sunday against the eighth-ranked Seahawks pass defense.
Justin Forsett scored his first touchdown as a Bronco last week, but could lose snaps and touches Sunday to rookie Devontae Booker against the Raiders with Denver eliminated from the playoffs and in talent evaluation mode.
DuJuan Harris will be in the backfield mix along with Shaun Draughn on Sunday, as the 49ers face the Seahawks with top running back Carlos Hyde (knee) on the shelf.
Jared Cook continues to share reps and targets with Richard Rodgers, giving him only a puncher's chance at exploiting a Lions defense that has allowed opposing tight ends to score 10 times this season.
Mike Gillislee rushed for a season-high 91 yards last week,but will remain behind LeSean McCoy on the depth chart in Week 17 against a New York Jets rushing defense allowing 100.9 yards per contest on the ground.