Le’Veon Bell will take on the Browns this Sunday, but there’s a strong possibility that the team will rest him, as the Steelers have clinched the third spot in the AFC, making this a meaningless game.
Jordy Nelson has multiple touchdown catches in two of his last three games entering Sunday night's showdown for the NFC North crown against the Lions, a defense he put 101 yards and two scores up against in a Week 3 meeting.
Steven Hauschka should get plenty of opportunities Sunday against a 49ers team that has allowed a league-high 30.3 points per game.
Ben Roethlisberger will have a Week 17 tilt against the Browns, though it’s possible that the team will choose to rest him in a meaningless game.
Ladarius Green will take on the Browns in Week 17 after missing last week’s game with a concussion, and it seems unlikely that the Steelers will use him in a game that has no playoff implications.
Chris Boswell will have a Sunday matchup against the Browns after attempting one or fewer field goal attempts in two of his last four games.
Jesse James will have a Week 17 tilt against the Browns, who have allowed four touchdowns to opposing tight ends over the last three weeks.
Aaron Rodgers has three or more touchdowns in two of his last three games and hasn't thrown an interception in six straight entering a Sunday night showdown with Detroit, whom he threw for four scores against in Week 3.
Tom Brady and the New England Patriots can clinch home field throughout the playoffs with a win on Sunday over the Miami Dolphins, whose defense has allowed 27 passing touchdowns in 2016, which is tied for 25th in the NFL.
Antonio Brown will have a Sunday tilt against the Browns, but it’s very possible that the team will significantly limit his playing time, due to the fact that the Steelers have clinched the third seed in the AFC playoffs.
DeSean Jackson has topped 100 yards in four of his past five games heading into Sunday's crucial matchup against a Giants team he loves to face.
Doug Baldwin just burned Arizona for 13 catches and 171 yards last week, so a strong encore is likely Sunday against a 49ers defense that has allowed a league-worst 30.3 points per game.
Odell Beckham has 504 yards and four touchdowns over the past five weeks, and will look to stay hot Sunday against cornerback Josh Norman and the 27th-ranked Redskins pass defense.
LeSean McCoy has four 100-yard games in his last five contests while scoring six touchdowns over that span, and will face a reeling New York Jets rushing defense in Week 17 that's allowing over 100 yards per game on the ground this season.
Jordan Howard has at least 99 total yards in eight straight games, a streak that started in his first matchup with Sunday's opponent, the Minnesota Vikings, whom he gashed for 153 yards and a score on 26 carries.
Brandin Cooks has 24 receptions for 418 yards over his past four games since turning in a duck against the Rams, but faces a Falcons secondary in Week 17 that held him to two receptions and eight yards in Week 3.
Marqise Lee looks to finish off a breakout season in Week 17 against the Indianapolis Colts' 25th-ranked rushing defense 273.7 ypg).
Mark Ingram is just 60 yards away from his first 1,000-yard season, and faces a Falcons defense on Sunday that’s allowed the eighth-most yards per attempt this season.
Delanie Walker will have to adjust to a new quarterback in Week 17 as Matt Cassel replaces the injured Marcus Mariota (fibula) against the Houston Texans, who rank third in yards allowed per game to tight ends (35.4 ypg).
Charles Clay has scored in three-straight games, and faces a suspect New York Jets passing defense on Sunday that's allowed 30 passing scores in 2016, which is tied for 30th in the NFL.
Bilal Powell should see the bulk of the carries Sunday against the Buffalo Bills, whose defense is allowing a subpar 133.5 rushing yards per game.
Sterling Shepard has scored six times in his past eight games, and has a good chance of finding the end zone once again Sunday against the 27th-ranked Redskins pass defense.
Stephen Gostkowski has five field goals over his last two games while not missing a kick in four-straight contests, and faces a Miami squad on Sunday that's allowing 23 points per tilt, which is 14th in the NFL.
Tyrod Taylor had three touchdown passes last weekend, and will face a reeling New York Jets defense on Sunday that's allowed 30 passing scores in 2016, which is tied for 30th in the NFL.
Michael Thomas is just 19 yards away from 1,000 yards in his rookie season, and leads all rookies in receptions, yards, touchdowns and any other receiving category you can think of; he's nearly a lock to reach his milestone Sunday against the Falcons.
Robbie Gould is likely to stay busy with New York's pass-oriented attack clashing with the league's 25th-ranked pass defense Sunday.
Matthew Stafford has failed to throw a touchdown pass in two straight games, but gets a Packers defense at home Sunday that ranks 30th in touchdown passes allowed, and one which he carved up for 385 yards and three scores in a Week 3 meeting.
Thomas Rawls is expected to be back from last week's shoulder bruise in time to exploit San Francisco's league-worst rushing defense in Week 17.
Cameron Brate injured his back last week on his second target, but if he can suit up, will be a strong play on Sunday against the permissive Panthers defense that’s allowed 12 touchdowns to opposing tight ends.
Nick Novak ranks second with 39 field-goal attempts and seventh in scoring with 8.1 points-per-game entering Week 17 against the Tennessee Titans' 19th-ranked scoring defense (24.1 ppg).
David Johnson has found pay dirt 20 times this season, and will be motivated to add to that total Sunday against a Rams team that surprisingly kept him from scoring back in Week 4.
Mason Crosby is averaging 9.3 points over the past three weeks heading into a matchup with a Lions defense that allowed 42 points last week and 34 to the Packers the last time these two faced off.
Zach Ertz has over 300 yards in his past four games combined, and should be able to stay on that pace Sunday against the 28th-ranked Cowboys pass defense.
Jimmy Graham is primed for another big game Sunday against a 2-13 49ers team that he burned for 100 yards and a touchdown back in Week 3.
Kirk Cousins faces the 22nd-ranked Giants secondary Sunday with a Redskins playoff berth potentially hanging in the balance.
Brandon LaFell will have a Sunday tilt against the Ravens after posting at least 91 receiving yards and three of his last four games.
Russell Wilson closes the regular season Sunday against a 49ers team that has allowed the most points in the league.
T.Y. Hilton looks to finish out a nice bounce-back season in Week 17 when the Indianapolis Colts face the three-win Jacksonville Jaguars, who rank sixth in yards allowed per game to wideouts (144.7 ypg).
Eli Rogers will face the Browns in Week 17, after averaging 79.5 yards along with one touchdown over his last two contests.
Drew Brees is just 142 yards away from his fifth 5,000-yard season, and faces the Falcons’ second-worst fantasy secondary on Sunday to accomplish it.
Adam Thielen has at least 86 yards in three of his last four games and has emerged as the Vikings top receiving threat entering a Week 17 finale against a Bears secondary that has allowed three receivers to top 93 yards in the last two games.
Justin Tucker will face the Bengals on Sunday after connecting on nine field goals over his last three games.
Cameron Meredith has scored or topped 100 yards in three straight games, seeing 33 targets in that span entering Sunday's season finale against a Vikings defense that has allowed six touchdown passes in the last two weeks.
Sammy Watkins is coming off his first 100-yard game of the season, and will face a suspect Jets secondary on Sunday that's allowing 249 passing yards per game, which is 20th in the league.
Mike Evans will look to cap off his career year against a Panthers secondary on Sunday that’s allowed a league-worst 291 receiving yards per game.
Greg Olsen has 16 receptions over his past three games, and will look to replicate his nine catch, 181 yard performance from Week 5 against the Bucs on Sunday.
Carson Wentz will close out his rookie season Sunday with a plus matchup against the 28th-ranked Cowboys secondary.
Eli Manning's Giants clinched a playoff spot last week, but he's still expected to be out there Sunday against a Redskins defense he burned for 350 yards back in Week 3.
Julian Edelman needs 45 receiving yards on Sunday for the second 1,000-yard season of his career, and will face a Miami Dolphins defense allowing 240 passing yards per contest, which is 13th in the NFL.
Adam Vinatieri ranks 10th with 7.9 points-per-game entering Week 17 against the Jacksonville Jaguars, who rank 26th in scoring defense (25.1 ppg).