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Eli Manning completed 24 of 39 pass attempts for 195 yards with two touchdowns and two interceptions last Sunday in a loss to the Pittsburgh Steelers, his fifth straight game with multiple touchdowns, a streak he hopes to continue this Sunday against a Dallas Cowboys defense that is tied for 21st in production allowed to opposing quarterbacks this season.
Trevor Siemian is on track to return to action after a one-game absence due to a foot injury, and gets a favorable matchup Sunday against a Titans defense allowing 270.3 passing yards a game, 26th in the league.
Jared Goff completed 14 of 32 passes for 161 yards, a touchdown and two interceptions against the New England Patriots last week, but will look to bounce back this week against an Atlanta Falcons defense that ranks last in the NFL in production allowed to opposing quarterbacks.
Bryce Petty has been handed the reins of the struggling New York Jets offense, and will square off on Sunday against a suspect San Francisco defense that's allowed 26 passing touchdowns in 2016, which is tied for 30th in the league.
Matt Barkley has played surprisingly decent in two starts, but faces a surging Lions pass defense that hasn't allowed a touchdown pass in two straight and only one multiple touchdown game since Week 6.
Sam Bradford has only one touchdown pass in his last two games and faces a second-ranked Jaguars defense on Sunday that allows 196 yards per game, having allowed one touchdown pass in their last three games while holding three of the last four quarterbacks they've faced to 166 yards or less.