Emmanuel Sanders has not topped 30 receiving yards in any of his last six games for the Bills, but in Week 18, he gets a Jets defense that ranks 31st in pass DVOA so far in 2021.
Zack Moss has not topped 60 total yards in any of his last eight games for the Bills, but in Week 18, he gets a Jets defense that ranks 26th in rush DVOA so far in 2021.
Randy Bullock has connected on 26 of 30 field-goal attempts for the Titans this season, and he'll look to close out the regular season on a high note in Week 18 against a Texans team that's allowing 26.5 points per game.
Ray-Ray McCloud has topped 35 yards just once this year for the Steelers, but in Week 18, he gets a Ravens defense that ranks 30th in pass DVOA so far in 2021.
Pat Freiermuth has scored in five of his last nine times out for the Steelers, and in Week 18, he gets a Ravens defense that ranks 30th in pass DVOA so far in 2021.
Chris Boswell has missed just four of his 37 field-goal tries this season for the Steelers, and in Week 18, he gets a Ravens defense that is giving up 23.5 points per game in 2021, ranking them in the middle of the pack.
Case Keenum threw for 199 yards and a touchdown in his lone start this year for the Browns, and in Week 18, he gets a Bengals defense that ranks 24th in pass DVOA so far in 2021.
Austin Hooper has topped 45 yards just once this season for the Browns, but in Week 18, he gets a Bengals defense that ranks 24th in pass DVOA so far in 2021.
Justin Fields is hoping to return from a two-week absence due to an ankle injury for the Bears in Week 18, where he'd face a Vikings defense that he posted 320 total yards against last time out, and one that allows 252.1 yards per game and 7.5 yards per attempt.
Samaje Perine has topped 45 total yards in a game just twice this year for the Bengals, but in Week 18, he gets a Browns defense that ranks 20th in rush DVOA so far in 2021.
Daniel Carlson has kicked at least three field goals in four of the last six games, giving him significant upside in Week 18 as the Raiders face a Chargers team allowing 26.5 points a game, tied for 26th in the league.
Rashard Higgins has topped 30 yards just twice this season for the Browns, but in Week 18, he gets a Bengals defense that ranks 24th in pass DVOA so far in 2021.
Anthony Schwartz has just nine catches all year for the Browns, but in Week 18, he gets a Bengals defense that ranks 24th in pass DVOA so far in 2021.
David Njoku has topped 40 yards just twice this year for the Browns, but in Week 18, he gets a Bengals defense that ranks 24th in pass DVOA so far in 2021.
Brett Maher has made at least three field goals in three of his last four games as the Saints head into a Week 18 matchup against Atlanta.
Joey Slye rebounded with three field goals last game for Washington and has a juicy matchup in Week 18 versus a reeling Giants squad allowing an average of 28.2 points during their current five-game losing streak.
Dontrell Hilliard mustered 78 scrimmage yards and a touchdown last week, establishing himself as Tennessee's preferred change-of-pace backfield option behind D'Onta Foreman heading into what could be a run-heavy Week 18 game against the Texans.
Deonte Harris earned only two targets in his return from a three-game suspension and he'll now head into a Week 18 matchup against an Atlanta defense that has allowed the seventh-most fantasy points to opposing wide receivers this season.
Chase McLaughlin has missed six of his 21 field-goal tries for the Browns this season, and in Week 18, he gets a Bengals defense that has allowed 22.2 points per game in 2021, ranking them in the middle of the pack.
Sammy Watkins does not have a catch in any of his last three games for the Ravens, and in Week 18, he gets a Steelers defense that ranks 13th in pass DVOA in 2021.
Younghoe Koo has made a pair of field goals in each of his last three games heading into Atlanta's Week 18 matchup against the Saints.
Cairo Santos has struggled for consistent opportunities in a low-scoring Bears offense, making multiple field goals just three times in his last seven outings heading into a Week 18 contest against a Vikings defense that's allowed 12 opposing kickers to go for at least eight points against them.
Nico Collins scored his first career touchdown two weeks ago with Brandin Cooks sidelined, but he has delivered modest production as Houston's No. 2 wide receiver with Cooks healthy, though perhaps a Week 18 matchup with a Titans defense that has allowed 2,966 yards to wide receivers - second-most in the league - will help Collins close out his rookie season on a high note.
Rashod Bateman has topped 35 yards just twice over his last seven games for the Ravens, and in Week 18, he gets a Steelers defense that ranks 13th in pass DVOA in 2021.
Ty Johnson could see a big uptick in touches if Michael Carter (concussion) is out for the Jets, and in Week 18, he'll get a Buffalo defense that ranks 15th in rush DVOA so far in 2021.
Evan McPherson has missed five of his 33 field-goal attempts this season for the Bengals, and in Week 18, he gets a Browns defense allowing 22.2 points per game, ranking them in the middle of the pack.
Taylor Heinicke has thrown multiple touchdown passes just twice in the last 11 games for Washington but will face a reeling Giants defense in Week 18 that's surrendered nine passing scores during its current five-game losing streak.
Andy Dalton managed only 4.9 yards per attempt in last week's start, but if Justin Fields (ankle) is unable to play for the Bears in Week 18, Dalton would be in a favorable spot against a Vikings defense that allows 7.5 yards per attempt and 28 TD passes to date.
Jared Goff remains uncertain to start for the Lions in Week 18 due to a knee injury, but should he gain clearance, he'll face a Green Bay defense that's allowed multiple touchdown passes in five of their last six games, and could rest starters at some point with the No. 1 seed already clinched.
Riley Patterson missed his first career kick for the Lions last week, but returning indoors, playing for an inefficient offense and having attempted three field goals in three of six starts, a bounce back is possible in Week 18 even against a stingy Packers' defense that's allowed only five opposing kickers to go for eight or more points against them.
Josiah Deguara has caught two or three passes in nine straight games for the Packers, but has only one score and has topped 35 yards just twice, making him a relatively known commodity in a Week 18 matchup against a Lions defense that's allowed 12 opposing tight ends to top 40 yards against them to date.
T.Y. Hilton comes into the Colts' Week 18 trip to Jacksonville riding a two-game touchdown streak, but the veteran wide receiver had just one touchdown in his previous seven appearances this season, so he'll be a boom-or-bust option as the Colts look to secure a playoff berth.
Robbie Gould has scored between five and 12 points in each of the 49ers' last nine games, giving him a decent scoring floor in a Week 18 matchup against a Rams team that's given up 7.8 points per game to opposing kickers over the last five weeks.
Zay Jones has seen at least seven targets in four straight games, amassing a 25-262-0 line on 32 targets over that stretch, and he should see solid volume again in Week 18 as the Raiders take on a Chargers defense that ranks in the middle of the pack in passing yards per game allowed and passing TDs allowed.
Jalen Guyton saw his three-game touchdown streak end last week, but he remains a big-play threat for the Chargers heading into a Week 18 clash with a Raiders defense that ranks 10th in passing yards per game allowed.
Geoff Swaim caught his third touchdown of the season last week, but he has surpassed 10 yards only once in his last five games, so Tennessee's top tight end will be a touchdown-dependent Week 18 option against a Texans defense that has allowed seven touchdowns to the position this season.
Tajae Sharpe will hope to return for the Falcons' Week 18 matchup against the Saints, though he has recorded more than two receptions in a game only three times this season.
Devontae Booker had nearly as many touches as Saquon Barkley last game for the Giants, though Barkley more than doubled Booker's production, meaning the latter should remain on the losing half of the timeshare heading into Week 18 versus a Washington defense allowing 105.1 yards per tilt on the ground, which is eighth in the NFL.
Damiere Byrd has managed only one catch in each of the Bears last two games, and with the return of Allen Robinson to health and in a low-volume passing attack, it likely takes a broken play for Byrd to exploit a Vikings secondary in Week 18 that's allowing 252.1 yards per game.
Nick Westbrook-Ikhine didn't record a catch last week and will slip to third on Tennessee's wide receiver depth chart in Week 18 against the Texans with Julio Jones back from the reserve/COVID-19 list, likely further dampening his modest usage.
Olamide Zaccheaus has recorded two or fewer receptions in each of Atlanta's last four games heading into a Week 18 matchup against the Saints.
Adam Trautman has seen his involvement in the Saints' offense dip in recent weeks as the Saints head into a Week 18 matchup against an Atlanta defense that has allowed only seven touchdowns to opposing tight ends this season.
Jauan Jennings has been held to fewer than 30 yards in each of the 49ers' last three games, making him a risky fantasy option in a Week 18 matchup against a Rams defense that's given up over 180 yards and the 13th-most fantasy points per game to opposing WRs over the last five weeks.
Albert Okwuegbunam has only two catches in the last two games with Drew Lock under center for the Broncos, and with Teddy Bridgewater not expected to clear the concussion protocols in time to play in Week 18, he'll be a risky option against a Kansas City defense that ranks in the middle of the pack in production allowed to TEs.
Lirim Hajrullahu has been accurate from short range across two games as the Panthers' kicker heading into a Week 18 matchup against Tampa Bay.
Jeremy McNichols played just six snaps last week, as his pass-catching skills are more useful when the Titans are playing from behind, and his role could remain limited in Week 18 as Tennessee's heavily favored against the 4-12 Texans.
DeeJay Dallas (thigh) took a backseat as the backup running back to Travis Homer in Seattle's last game, making him a risky fantasy option in a Week 18 matchup against a Cardinals defense that's allowed 105 rushing yards per game and the 11th-fewest fantasy points to opposing RBs over the last five weeks.
Josh Reynolds will return after a one-week absence for the Lions in Week 18, reprising his role as a field stretcher (averaging 17.3 yards per catch in four of five) in a matchup against a Packers defense that allows just 6.5 yards per pass attempt.
Ke'Shawn Vaughn could serve as Buccaneers' lead back in Week 18, but he'll have to play through a ribs injury while also facing a Carolina defense that has allowed the fourth-fewest fantasy points per game to opposing running backs this season.
Jonnu Smith has topped 30 yards in just three games this season for the Patriots, but in Week 18, he'll get a Dolphins defense that ranks ninth in pass DVOA so far in 2021.