Antonio Brown will have a Sunday tilt against the Browns, but it’s very possible that the team will significantly limit his playing time, due to the fact that the Steelers have clinched the third seed in the AFC playoffs.
Jordy Nelson has multiple touchdown catches in two of his last three games entering Sunday night's showdown for the NFC North crown against the Lions, a defense he put 101 yards and two scores up against in a Week 3 meeting.
Marqise Lee looks to finish off a breakout season in Week 17 against the Indianapolis Colts' 25th-ranked rushing defense 273.7 ypg).
Adam Thielen has at least 86 yards in three of his last four games and has emerged as the Vikings top receiving threat entering a Week 17 finale against a Bears secondary that has allowed three receivers to top 93 yards in the last two games.
Julian Edelman needs 45 receiving yards on Sunday for the second 1,000-yard season of his career, and will face a Miami Dolphins defense allowing 240 passing yards per contest, which is 13th in the NFL.
Odell Beckham has 504 yards and four touchdowns over the past five weeks, and will look to stay hot Sunday against cornerback Josh Norman and the 27th-ranked Redskins pass defense.
Sammy Watkins is coming off his first 100-yard game of the season, and will face a suspect Jets secondary on Sunday that's allowing 249 passing yards per game, which is 20th in the league.
Mike Evans will look to cap off his career year against a Panthers secondary on Sunday that’s allowed a league-worst 291 receiving yards per game.
DeSean Jackson has topped 100 yards in four of his past five games heading into Sunday's crucial matchup against a Giants team he loves to face.
Brandin Cooks has 24 receptions for 418 yards over his past four games since turning in a duck against the Rams, but faces a Falcons secondary in Week 17 that held him to two receptions and eight yards in Week 3.
T.Y. Hilton looks to finish out a nice bounce-back season in Week 17 when the Indianapolis Colts face the three-win Jacksonville Jaguars, who rank sixth in yards allowed per game to wideouts (144.7 ypg).
Sterling Shepard has scored six times in his past eight games, and has a good chance of finding the end zone once again Sunday against the 27th-ranked Redskins pass defense.
Michael Thomas is just 19 yards away from 1,000 yards in his rookie season, and leads all rookies in receptions, yards, touchdowns and any other receiving category you can think of; he's nearly a lock to reach his milestone Sunday against the Falcons.
Brandon LaFell will have a Sunday tilt against the Ravens after posting at least 91 receiving yards and three of his last four games.
Cameron Meredith has scored or topped 100 yards in three straight games, seeing 33 targets in that span entering Sunday's season finale against a Vikings defense that has allowed six touchdown passes in the last two weeks.
Eli Rogers will face the Browns in Week 17, after averaging 79.5 yards along with one touchdown over his last two contests.
Doug Baldwin just burned Arizona for 13 catches and 171 yards last week, so a strong encore is likely Sunday against a 49ers defense that has allowed a league-worst 30.3 points per game.
Golden Tate has at least six catches in four straight games entering a season finale matchup with Green Bay's 29th ranked pass defense that allows 265 yards per game.
DeAndre Hopkins' production didn't change with the quarterback switch from Brock Osweiler to Tom Savage, so we should expect a run-first attack out of the Houston Texans in Week 17 against the Tennessee Titans.
Alshon Jeffery has at least eight target in six straight games and is averaging 90.5 yards in his two games since returning from suspension, seemingly giving him a safe floor even if he's matched up exclusively with Vikings corner Xavier Rhodes on Sunday.
Rishard Matthews looks to finish off his breakout season in Week 17 against the Houston Texans, who rank second in receiving defense (218.3 ypg).
Kenny Stills has found the end zone in three-straight games, but will face a New England defense in Week 17 that's yielded 19 passing scores in 2016, which is tied for seventh in the NFL.
Kelvin Benjamin snapped his cold streak (five receptions for 49 yards over his previous three games) to catch his second touchdown since Oct. 2, but the Panthers’ passing game makes him tough to trust on Sunday against the Bucs, even as they’ve allowed the 10th-most receiving yards in the league.
Jamison Crowder closes out the regular season Sunday against the 22nd-ranked Giants secondary.
J.J. Nelson takes a four-game scoring streak into Sunday's season finale against the ninth-ranked Rams pass defense.
Tyler Boyd will face the Ravens on Sunday after catching five passes for 62 yards in his last meeting against them.
Tyreek Hill failed to catch any of his five targets last week but scored his third rushing TD in five games, and the Chiefs should be committed to getting the ball in his hands once again Sunday as they look to keep their chances of an AFC West title alive.
Ty Montgomery has at least 12 touches in three straight games, but faces a Lions defense on Sunday that has allowed opposing backs to score only five times this year, and only six backs to top 70 yards.
Willie Snead has more than 800 receiving yards despite being the Saints’ third receiver, but that role makes him more of a toss-up than the two above him on the depth chart as he’s still liable for two reception, 21 yard clunkers like last week when he plays the Falcons in Week 17.
Davante Adams has only six catches and 69 yards over the last two weeks entering a matchup against a Lions secondary that has not allowed more than 212 yards passing in three straight games.
Allen Robinson is coming off his best game of the season and looks to build off that in Week 17 against the Indianapolis Colts, who rank 18th in yards allowed per game to wideouts (160.8 ypg).
Jarvis Landry had a two-game streak of 100-yard outings snapped last weekend, and will face a New England defense in Week 17 that's allowing 240 passing yards per tilt, which is 14th in the league.
Jordan Matthews is battling through an ankle injury, but should still be able to find success against a 28th-ranked Cowboys secondary that has allowed 264.7 passing yards per game.
DeVante Parker posted 85 yards and a touchdown last weekend, and will face a New England defense on Sunday that's allowing 240 passing yards per game, which is 14th in the NFL.
Pierre Garcon has recorded between 50 and 100 yards on 10 different occasions this season, and should fall in that range once again Sunday against the 22nd-ranked Giants secondary.
Ted Ginn has 50 receptions for just the second time in his ten-year career, and faces a Bucs secondary on Sunday that’s allowed the tenth-most receiving yards in the league.
Larry Fitzgerald hasn't scored since Week 5, and is unlikely to find the end zone Sunday against the ninth-ranked Rams pass defense with J.J. Nelson emerging as the bigger touchdown threat among Cardinals receivers.
Jeremy Maclin was held in check last week by the Broncos' secondary, but should be more productive Sunday against a Chargers defense that he found the end zone against in Week 1.
With backup Matt Cassel starting Week 17, fellow second-teamer Harry Douglas, who had a season-high six targets last week, could be in line or additional work in the regular-season finale against the Houston Texans.
Robert Woods has fallen down the depth chart in terms of targets, though he could find some extra room in Week 17 against a soft Jets passing defense that's allowed 30 passing touchdowns in 2016.
Cole Beasley has cooled off down the stretch, and is unlikely to pick things back up Sunday in Philadelphia with the Cowboys resting key contributors.
Marvin Jones has one catch in three of his last six games and has shown no signs of reclaiming his early season success entering an otherwise exploitable matchup with Green Bay's 29th ranked pass defense.
Dontrelle Inman saw double-digit targets last week for just the second time this season, but remains a risky play Sunday against a Chiefs pass defense that ranks third in QB rating against.
Hogan has just two catches in his last two games, and faces a Miami defense on Sunday that's allowing just 240 passing yards per contest, which is 13th in the NFL.
Terrelle Pryor will take on the Steelers this Sunday after posting a total of 58 yards over his last three games while he’s battling through a finger injury that could require off-season surgery.
Jermaine Kearse might get a few more targets in the wake of Tyler Lockett's broken leg, but he'll still be a lower-tier option Sunday in San Francisco.
Entering the final week of the regular season and with no chance of qualifying for the postseason, Donte Moncrief is a big question mark for Week 17 against the Jacksonville Jaguars' third-ranked receiving defense (220.4 ypg) due to a shoulder injury.
Adam Humphries caught a single pass last week, but could return to the game plan on Sunday against the Panthers if Cameron Brate is unable to play with his back injury.
Will Fuller will be the second wideout for the Houston Texans, who have become a run-heavy team, entering Week 17 against the Tennessee Titans' 31st ranked receiving defense (287.1 ypg).
Malcolm Mitchell has just four catches for 43 yards over his last two games, and faces a Miami defense on Sunday that's allowing 240 passing yards per game, which is 13th in the league.