Tom Brady has tossed three touchdown passes in back-to-back games and faces a reeling Miami Dolphins squad that's allowed 16 throwing scores in 2017, which is in the bottom half of the NFL.
Jimmy Graham has seven touchdowns in his past six games, and should have no trouble getting into the end zone again Sunday against a 49ers team that's allowed a tight end to score in each of its past four games.
Russell Wilson struggled against the 49ers back in Week 2, but his 21:7 touchdown to interception ratio suggests he's made the proper advantage to thrive in Sunday's rematch.
Jarvis Landry has scored in six of the last seven games and will face a New England Patriots defense that's allowed 17 passing scores in 2017, which is 25th in the NFL.
Doug Baldwin's heated up with 389 yards and three touchdowns over the past five weeks, and should find further success Sunday in San Francisco against a defense that's surrendering 26.0 points per game.
Todd Gurley has over 1,200 yards from scrimmage and 11 touchdowns in 10 games, so expect a huge performance from him Sunday in what should be a high-scoring affair against the Saints.
LeSean McCoy scored twice this past Sunday and will face a Kansas City Chiefs defense allowing 131.1 rushing yards per game, which is 29th in the NFL.
A.J. Green has touchdowns in back-to-back games, but now he faces a Cleveland Browns defense Sunday that's allowed the eighth fewest receiving yards in the league to opposition wide receivers.
Vernon Davis will be taking on the Giants on Thursday to face a defense that has allowed the most fantasy points to tight end position this season.
Antonio Brown is coming off a 10-catch, 144-yard, three-touchdown game last week, and now he faces a Green Bay Packers defense Sunday that allows the sixth most fantasy points to opposing receivers.
Julio Jones is in line for another big game—touchdown or otherwise—when he faces off in Week 12 against the Bucs’ second-worst secondary, allowing 276 passing yards per game.
A season-ending Achilles injury to D'Onta Foreman should grant more touches for Lamar Miller in Week 12 against the Baltimore Ravens' 26th-ranked run defense (120.8 YPG).
Kirk Cousins has a Thursday tilt against the Giants in an excellent matchup against a defense that’s in the bottom-five in terms of production allowed to opposing quarterbacks.
Jamison Crowder will have an excellent Thursday matchup against the Giants, who have allowed six touchdowns to opposing wide receivers over their last four games.
Kareem Hunt hasn't found the end zone since Week 3, but his drought could end Sunday at home against a Bills defense that's surrendered a league-worst 13 rushing TDs this season to running backs.
Delanie Walker has been productive through a four-game stretch dealing with injuries, but is healthy again for Week 12 against the Indianapolis Colts, who rank 25th at 11.6 yards per reception allowed to tight ends.
Rishard Matthews enters Week 12 on a bit of a streak (113 yards in Week 11, two TDs in last three games) and could build on that against the Indianapolis Colts, who rank 30th in yards allowed to wide receivers (186.1 YPG).
Mike Wallace has touchdowns in back-to-back games, and now he faces a Houston Texans defense Sunday that have allowed the third most fantasy points to opposing receivers.
Cam Newton is coming off his best game of the season (four passing touchdowns and 95 yards rushing) and faces the Jets’ lackluster secondary in Week 12 that’s conceded 20 passing touchdowns, tied for the fourth-worst mark in the league.
Joe Flacco has just nine touchdown passes on the season, but he faces a Houston Texas defense this week that has allowed an average of 343 yards and three touchdowns to QBs over their last four games.
Mark Ingram made the most of limited work (12.2 yards per carry on 11 carries) and faces the Rams’ fifth-worst run defense on Sunday.
Unable to push the ball down the field last week, Matt Ryan will likely have more room to throw in Week 12 against Tampa’s second-worst pass defense, allowing 276.3 passing yards per game.
Dion Lewis has established himself as the top running back for the New England Patriots, and the Miami Dolphins are allowing 116.2 rushing yards per game in 2017, which is 20th in the NFL.
Mohamed Sanu snagged a highlight reel touchdown grab against the Seahawks and could find more room in Week 12 against the Bucs’ second-worst secondary, allowing 276 passing yards per game.
Melvin Gordon has rushed for at least 80 yards and a touchdown in three of the last five games, and now he faces a Cowboys defense Thursday that allows 4.6 yards per carry, 28th in the league.
T.Y. Hilton has had a feast-or-famine season and has a tasty matchup Week 12 against the Tennessee Titans, who have surrendered 15 touchdowns to wide receivers (31st).
Devin Funchess caught a pair of touchdowns in the Panthers’ last game heading into the bye and faces a Jets secondary in Week 12 that’s allowed 20 passing touchdowns in 10 games this season.
Christian McCaffery has five touchdowns over his last six games prior to the bye week and has shown an ability to produce even with limited touches, something that could be key in Week 12 against the Jets’ tenth-worst run defense that’s also allowed the fourth-most passing touchdowns this season.
Kenny Stills exploded for 180 yards and a touchdown this past weekend and has always had a superb rapport wth backup Matt Moore, who appears likely to start Sunday against a New England Patriots defense that's allowed 17 passing scores in 2017, which is 25th in the NFL.
Latavius Murray is averaging 5.1 yards per carry over his last two outings while scoring four times in as many games entering Thursday's contest against a Lions defense that's allowed 4.4 yards per carry and 12 rushing touchdowns, the second highest total in the league.
Brandin Cooks is coming off his best game as a member of the Patriots, is averaging more than nine targets over the last three contests and will face a reeling Miami Dolphins defense allowing 220 passing yards per tilt, which is 15th in the NFL.
Adam Thielen has 96 yards or more in four of his last five games while scoring in three straight, but faces a Lions pass defense Thursday that hasn't allowed a receiver to top 58 yards in three straight while holding Thielen himself to 59 yards in Week 4.
Jared Cook caught a season-low two passes in Week 11, but he seems poised for a rebound Sunday at home against a Broncos defense that's allowing almost 76 receiving yards a game to opposition tight ends, second highest in the league.
Keenan Allen is coming off his best game of the season, and now he faces a Cowboys defense Thursday which ranks in the bottom 10 in fantasy points allowed to opposition wide receivers.
Leonard Fournette told reporters following Week 11's win that he'll be dealing with an ankle injury for the rest of the season, so prepare accordingly Week 12 when the Jaguars head to the desert for matchup against the Arizona Cardinals, who allowed 134 yards rushing last week.
Rob Gronkowski was largely held in check this past Sunday but will have a favorable matchup with a Miami Dolphins defense that's allowed 16 passing scores in 2017, which is in the bottom half of the NFL.
Alvin Kamara caught six more passes lsat week to bring his total up to 48 on the season with seven total touchdowns and faces the Rams’ fifth-worst run defense in Week 12, and he could see significant work as a receiver.
DeAndre Hopkins has thrived against all opponents and should produce similarly Week 12 against the Baltimore Ravens, who rank fourth in yards allowed to wide receivers (119.4 YPG).
Sterling Shepard will have a Thursday meeting against the Redskins, as he’ll hope to return to the lineup after missing last week’s game due to migraines.
Le'Veon Bell has failed to crack 80 rushing yards in three straight games, but he still leads the league in carries and now faces a Green Bay defense Sunday that allows the 10th most fantasy points to running backs.
O.J. Howard caught his fourth touchdown of the season last week and seemed to build a nice rapport with Ryan Fitzpatrick, which could pay dividends in Week 12 against the Falcons’ defense that allowed a touchdown to Jimmy Graham last week and seven receptions to Jason Witten the previous week.
Evan Engram has a Week 12 tilt against a Washington defense that has allowed at least 59 yards to three different tight ends over the past five weeks.
Duke Johnson is leading the Browns in receiving this year and faces a Bengals defense Sunday that allows 6.3 catches and 45.5 receiving yards per game to opposing RBs.
Tevin Coleman ran for just 2.2 yards per carry against the stingy Seahawks defense and could be similarly stifled in Week 12 against the Bucs’ top-half run defense, but will have the benefit of being the every down back with Devonta Freeman unlikely to play again this week.
The Tennessee Titans' offense has been inconsistent this season and one can point to Marcus Mariota's 8:10 TD:INT as a factor, but he has a favorable Week 12 matchup against the Indianapolis Colts' 30th-ranked pass defense (274.5 YPG).
Emmanuel Sanders caught only two of eight targets in Week 11, but with Paxton Lynch taking over under center he could rebound Sunday on the road against a Raiders defense that's allowed 261.3 passing yards a game, 25th in the league.
Dez Bryant will have a Week 12 matchup against the Chargers, who have not allowed an opposing wide receiver to post more than 70 yards against them over their last five games.
Demaryius Thomas scored for the third straight game in Week 11, but he'll need to show the same chemistry with new starting quarterback Paxton Lynch if he's going to stay productive Sunday on the road against a Raiders defense that's allowed 261.3 passing yards a game, 25th in the league.
Tyler Kroft has just five catches across his last three games, but he faces a Cleveland Browns defense Sunday that allows the third most fantasy points to opposing tight ends.
Corey Davis has had a few rookie learning moments over the past two games, but remains a high-volume target entering Week 12 against the Indianapolis Colts, who rank 30th in yards allowed to wide receivers (186.1 YPG).