Pat Freiermuth has scored in five of his last nine times out for the Steelers, and in Week 18, he gets a Ravens defense that ranks 30th in pass DVOA so far in 2021.
Zach Ertz is averaging 11 targets over Arizona's last three games, giving him an expected high-scoring floor in a Week 18 matchup against a Seattle defense that's allowed 70 yards per game and the fourth-most fantasy points to opposing TEs over the last five weeks.
Dawson Knox has nine touchdowns for the Bills this season, and in Week 18, he gets a Jets defense that ranks 31st in pass DVOA so far in 2021.
Austin Hooper has topped 45 yards just once this season for the Browns, but in Week 18, he gets a Bengals defense that ranks 24th in pass DVOA so far in 2021.
David Njoku has topped 40 yards just twice this year for the Browns, but in Week 18, he gets a Bengals defense that ranks 24th in pass DVOA so far in 2021.
Noah Fant is coming off his most productive game since Week 6, but the Broncos' tight end may not be able to repeat the performance in Week 18 against a Kansas City defense that ranks in the middle of the pack in production allowed to TEs.
Josiah Deguara has caught two or three passes in nine straight games for the Packers, but has only one score and has topped 35 yards just twice, making him a relatively known commodity in a Week 18 matchup against a Lions defense that's allowed 12 opposing tight ends to top 40 yards against them to date.
George Kittle has been a feast-or-famine producer for the 49ers over the last five weeks, and he'll continue to have upside potential despite a Week 18 matchup against a Rams defense that's given up the fourth-fewest fantasy points to opposing TEs over the last four weeks.
Travis Kelce has scored three touchdowns in the last two games, but he could have trouble reaching the end zone again in Week 18 as Kansas City faces a Broncos defense that's given up only one TD to a tight end all season.
Mark Andrews is averaging over 115 yards with a touchdown over his last four games for the Ravens, and in Week 18, he gets a Steelers defense that ranks 13th in pass DVOA in 2021.
James O'Shaughnessy missed Jacksonville's previous game due to a hip injury, but the starting tight end will try to return for the Week 18 season finale against a Colts defense that's one of six in the league that has allowed over 1,000 yards to tight ends.
Jack Doyle returned from knee and ankle injuries last week, and he'll split tight end duties for the Colts with Mo Alie-Cox in Week 18 against a Jaguars defense that has held tight ends to five touchdowns this season while being more vulnerable to running backs and receivers.
Darren Waller has missed the Raiders' last five games with a knee injury, but if he's able to return in Week 18, he'll get a juicy matchup against a Chargers defense that's allowed the most receiving yards and touchdowns in the league to tight ends this season.
Geoff Swaim caught his third touchdown of the season last week, but he has surpassed 10 yards only once in his last five games, so Tennessee's top tight end will be a touchdown-dependent Week 18 option against a Texans defense that has allowed seven touchdowns to the position this season.
Kyle Pitts got off to a hot start against Buffalo but exited with a hamstring injury, calling into question his availability for Atlanta's Week 18 matchup against the Saints
Jared Cook missed last week's game while on the COVID-19 list, but if he's able to return to action in Week 18 he could have some appeal as the Chargers take on a Raiders defense that ranks in the bottom 10 in catches, yards and TDs allowed to tight ends.
Tommy Tremble has surpassed two receptions in only one game this season heading into a Week 18 matchup against a Tampa Bay defense that has allowed the fifth-most receptions to opposing tight ends this season.
John Bates has seven targets, 80 receiving yards and a touchdown over his last two games for Washington and could be a sneaky play in Week 18 versus a Giants defense that's allowed nine passing touchdowns over their last five outings.
Hunter Henry has nine touchdowns this year for the Patriots, but in Week 18, he'll get a Dolphins defense that ranks ninth in pass DVOA so far in 2021.
Tyler Higbee has posted at least 41 yards in each of the last three games he's played for the Rams, and he'll likely continue to see targets in a Week 18 matchup against a 49ers defense that's allowed 43 yards per game and the ninth-fewest fantasy points to opposing TEs over the last five weeks.
Albert Okwuegbunam has only two catches in the last two games with Drew Lock under center for the Broncos, and with Teddy Bridgewater not expected to clear the concussion protocols in time to play in Week 18, he'll be a risky option against a Kansas City defense that ranks in the middle of the pack in production allowed to TEs.
Adam Trautman has seen his involvement in the Saints' offense dip in recent weeks as the Saints head into a Week 18 matchup against an Atlanta defense that has allowed only seven touchdowns to opposing tight ends this season.
Brock Wright will return after a one-game absence for the Lions in Week 18, and while he's taken over as the team's top tight end, it's netted just six catches and 24 yards in three games, giving him minimal potential against a Packers defense that's allowed eight opposing tight ends to go ofr 47 yards or more against them to date.
Cole Kmet has at least five targets in each of the Bears last five games, but has topped 49 yards only three times all season while failing to score, giving him minimal at best upside in a Week 18 finale against a Vikings defense that's allowed five touchdowns to the position since Week 11.
C.J. Uzomah has topped 40 yards just three times this year for the Bengals, and in Week 18, he gets a Browns defense that ranks 11th in pass DVOA so far in 2021.
Rob Gronkowski returned to form in Sunday's win over the Jets, but he may not see the field much in Tampa Bay's Week 18 matchup against Carolina to ensure he is fully healthy for a potential playoff run.
Gerald Everett has received four or five targets in each of Seattle's last three games, giving him potential for a solid scoring floor in a Week 18 matchup against a Cardinals defense that's allowed the fifth-fewest fantasy points to opposing TEs over the last five weeks.
Jonnu Smith has topped 30 yards in just three games this season for the Patriots, but in Week 18, he'll get a Dolphins defense that ranks ninth in pass DVOA so far in 2021.
Dallas Goedert has led the Eagles in receiving in three of the last four games but it remains to be seen how much he will play in Week 18 versus the Cowboys as both teams have locked up playoff spots and can only maneuver slightly in terms of seeding; if Goedert plays the majority of the contest, he will face a Dallas defense allowing 242.7 passing yards per tilt, which is 24th in the NFL.
Foster Moreau has posted modest numbers the last five games while Darren Waller has been sidelined, but if he gets another start for the Raiders in Week 18, it'll come against a Chargers defense that's allowed the most receiving yards and touchdowns in the league to tight ends this season.
Mike Gesicki has not topped 55 yards or scored in any of his last eight games for the Dolphins, and in Week 18, he gets a Patriots defense that ranks third in pass DVOA this season.
Tyler Conklin hasn't scored for the Vikings since Week 10, going for 35 yards or less in four of seven games since with a ceiling of 56 yards, creating a low floor/low ceiling option in Week 18 against a Bears' defense that's allowed only three opposing tight ends to top 45 yards against them to date, and one that held him to one catch for seven yards earlier in the year.
Dalton Schultz has a staggering 27 targets over the last three games but could be rested in Week 18 versus the Eagles as Dallas cannot likely alter its playoff seeding in any meaningful capacity.
Evan Engram recorded one of only four receptions for the Giants last game, and Daniel Jones is not walking through that door in Week 18, leaving Engram as a dismal option even against a suspect Washington defense allowing 265.6 passing yards per tilt, which is 30th in the NFL.
Pharaoh Brown continues to lead Texans' tight ends in snaps, but rookie Brevin Jordan does most of the pass catching at the position while Brown's used in a blocking role, and that should remain the case in Week 18 against Tennessee.
Will Dissly (heel) has posted fewer than 10 yards in three of Seattle's last four games, making him a shaky fantasy option in a Week 18 matchup against a Cardinals defense that's allowed the ffith-fewest fantasy points to opposing TEs over the last five weeks.
Brevin Jordan has struggled to stay consistently involved in Houston's offense while ceding the majority of snaps to Pharaoh Brown, but Jordan will look to finish his season on a high note in Week 18 against a Titans defense that has limited tight ends to three touchdowns.
Tyler Kroft has yet to top 40 receiving yards in an outing this season for the Jets, and in Week 18, he'll get a Buffalo defense that ranks second in pass DVOA so far in 2021.