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Indianapolis Colts earned a 232.08-94.96 win to hand Las Vegas Raiders their sixth straight loss to open the season. Indianapolis Colts nabbed a 178.98-point lead early Sunday afternoon behind standout showings from Matt Ryan (49.38 points) and Michael Pittman Jr. (30.9) and never looked back. Kenyan Drake (29.2 points) and Matthew Stafford (18.26) were the leaders for Las Vegas Raiders in the loss. Indianapolis Colts (2-4) will look to keep it rolling against Denver Broncos, while Las Vegas Raiders (0-6) will meet Tennessee Titans in an effort to develop some positive momentum.