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San Francisco 49'ers earned a 260.68-194.80 win to hand LA Rams their fifth straight loss. LA Rams nabbed a 40.20-point lead on Thursday behind a combined 28.8 points from Bobby Wagner (14 Tackles) and Cam Akers (42 Rush Yds, 1 Rush TD). But San Francisco 49'ers held the lead the rest of the way, powered by , who for 33.1 points, and Donovan Peoples-Jones, who caught 8 passes for 114 yards (24.4 points). This marks the second time this season San Francisco 49'ers have knocked off LA Rams, after winning 251.74-212 in their last matchup. San Francisco 49'ers ends the season on a high note, but they'll miss the postseason with a record of 6-8. LA Rams will also be home for the playoffs, finishing at 2-12.