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Both teams were hampered by starters who put up 0 points, but Indianapolis Colts were able to persevere and earn the win, coming from behind to earn a 222.02-210.10 victory over Detroit Lions. Despite trailing 202.60-185.92 heading into Monday night, Indianapolis Colts came storming back behind Austin Ekeler, who racked up 132 yards from scrimmage for 21.2 points, and Hunter Henry, who caught 6 passes for 69 yards (14.9 points). DJ Chark Jr. (8 Rec, 104 Rec Yds, 2 Rec TDs) and Christian McCaffrey (70 Rush Yds, 121 Rec Yds) were the leading scorers for Detroit Lions in defeat. Indianapolis Colts (8-3) will look to build on their success against Cincinnati Bengals, while Detroit Lions (8-3) meet Houston Texans in an effort to get back on track.