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There's no easy way to put it, Indianapolis Colts dropped the ball, at least based on projections, as New York Giants earned a 159.44-150.52 win. Indianapolis Colts took a 16.30-point lead on Thursday, but New York Giants held the lead the rest of the way. They were led by Patrick Mahomes, who passed for 446 yards and 3 touchdowns for 35.84 points, and Darius Slayton, who caught 10 passes for 121 yards and 2 touchdowns (34.1 points). Jameis Winston (22.32 points) and T.J. Watt (19.5) led the way for Indianapolis Colts in the loss. New York Giants (2-8) will look to keep it rolling against Chicago Bears, while Indianapolis Colts (7-3) will face Detroit Lions in an effort to develop some positive momentum.