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Detroit Lions won their fourth game in a row to open the season with a hard-fought victory over Indianapolis Colts, earning a 279.98-257.46 win. Detroit Lions never trailed in this one after grabbing a 32.70-point lead on Thursday behind Cooper Kupp (37.2 points) and Eric Kendricks (6). Andrew Luck (464 Pass Yds, 4 Pass TDs, 11 Rush Yds) and DeAndre Hopkins (10 Rec, 169 Rec Yds, 1 Rec TD) were the leaders for Indianapolis Colts in the loss. Detroit Lions (4-0) will look to keep it rolling against Miami Dolphins, while Indianapolis Colts (2-2) attempt to right the ship against Chicago Bears.