Kirk Cousins is primed for another huge performance against a Browns team that's allowing 294.3 passing yards per contest considering that he has surpassed that mark in every game this season.
DeSean Jackson's big play ability makes him a strong play Sunday against a 25th-ranked Browns pass defense that has given up more than its fair share of long gains.
Melvin Gordon scored his fourth TD of the season in Week 3 and gets a premium matchup Sunday at home against a Saints defense allowing a league-worst 149.3 rushing yards per game so far.
Terrelle Pryor will face Washington on Sunday, and it’s possible that he’ll continue to see snaps as a Wildcat quarterback, which could give him major upside this week.
Josh Lambo connected on three field goals in Week 3 and gets a very favorable matchup Sunday at home against a Saints defense that's allowed 32.0 points per game so far, second-worst in the league.
Travis Benjamin has averaged 19.7 yards per catch over the last two games and should be explosive once again Sunday at home against a Saints defense allowing nearly 300 passing yards a game so far.
Jamison Crowder already has 16 catches for 175 yards and two touchdowns this season, and likely won't slow down Sunday against a Browns team allowing 294.3 passing yards per game.
Dan Bailey missed one against Chicago, but should be able to rebound Sunday against a 49ers team that has been unimpressive since a Week 1 shutout.
Jordan Howard has an inviting matchup against a Lions defense which is allowing a league-high 5.1 yards per carry, and would see a boost in appeal should Jeremy Langford (ankle) miss the contest.
Kyle Rudolph has seen eight targets or more in all three games, catching two touchdowns, but faces a Giants defense on Monday night that has yet to allow a tight end to reach the end zone.
Isaiah Crowell has a Sunday contest against a Washington defense that has allowed six touchdowns to running backs through three games this season.
Jeremy Hill has a Thursday matchup against a Dolphins’ defense that allowed 123 rushing yards to LaGarrette Blount in Week 2 and then 148 yards to the Browns’ duo of Isaiah Crowell and Duke Johnson last week.
Joe Flacco will be at home to take on a Raiders’ defense that he had 384 passing yards and two touchdowns against when facing them in 2015.
Justin Tucker will take on the Raiders in Week 4 after making all nine of his field goal attempts over the first three weeks of the season.
Marvin Jones is averaging 22.7 yards per catch and has popped for at least one catch of 30+ yards weekly heading into a matchup against a Bears defense that is allowing only 214 yards per game through the air.
Dak Prescott has scored on the ground in back-to-back games, which makes him a solid Week 4 option against a 49ers team that has struggled to contain dual-threat quarterbacks.
Cole Beasley doesn't make many big plays, but rookie quarterback Dark Prescott should continue to look for him early and often Sunday against the 49ers after completing 20 passes for 213 yards to him through three weeks.
Dennis Pitta will face a Raiders’ defense on Sunday that has allowed at least 59 receiving yards to three different tight ends this season.
John Brown will look to follow last week's 70-yard performance with another strong effort Sunday against a Rams team that gave up 94 yards per game to him last season.
Pierre Garcon has been outplayed by both DeSean Jackson and Jamison Crowder among Redskins wide receivers, but could still put up big numbers Sunday against Cleveland's 25th-ranked pass defense.
Mike Wallace have a Sunday contest against the Raiders who have allowed three different wide receivers to post at least 106 yards and a touchdown against them in 2016.
After missing last week with a toe injury, Willie Snead will look to return on Sunday against the Chargers, who’ve allowed 325 or more passing yards to each of their first three opponents.
Fozzy Whittaker will look for more than five carries as he’s just a week removed from his 100-yard performance against the 49ers for Sunday’s divisional matchup against the Falcons, who allowed the sixth-most fantasy points to opposing running backs in 2015.
Zach Miller's value in Week 4 could come down to who starts under center, as he was a favorite check down target of Brian Hoyer's last week, against a Lions defense that has allowed a league-high 10 touchdown passes, five of which have gone to tight ends.
Julian Edelman may struggle if Jacoby Brissett lines up under center Sunday against the Bills, as the game plan will be geared more towards running the football, though Jimmy Garappolo may play despite a shoulder ailment.
Giovani Bernard will take on the Dolphins on Thursday night after catching 16 passes for 141 yards and a touchdown in three games this season.
Vance McDonald (hip) is a solid play if he suits up Sunday against Dallas' 23rd-ranked pass defense.
Cameron Brate caught two touchdowns last week and may be key in unlocking Denver’s tough defense, as they allowed the 11th-most fantasy points to opposing tight ends last season.
Jacob Tamme saw his production dip after 11 receptions for 126 yards in the first two weeks, but faces a Panthers' defense that’s allowed 145 yards and two scores to the opponent's featured tight end over the past two weeks.
Cairo Santos remains perfect on the season and should have a productive game Sunday against a Steelers defense that ranks in the middle of the pack with 22.0 points allowed per game in 2016.
Dan Carpenter kicked two field goals and three extra points last weekend, though will face a New England defense on Sunday that allows just 15 points per game.
Charles Sims will be a strong play for the Bucs on Sunday against the Broncos after they allowed 143 yards and 4.9 yards per carry to the Bengals last weekend.
Jeremy Maclin is coming off his worst game of the season in Week 3, but should be more productive Sunday against a Steelers defense that ranks 31st in passing yards allowed so far.
Chris Boswell will match up against the Chiefs on Sunday night, though he has just four field goal attempts in three 2016 contests.
Dwayne Washington is the best bet in a limited rushing offense, and faces a Bears defense that ranks second-to-last against the run, allowing 142.7 yards per game
Michael Floyd is one of three viable Cardinals receivers Sunday against a Rams defense that has skated by on weak competition thus far, but his status is uncertain early in the week as he's entered the league's concussion protocol.
Orlean Darkwa could play a major role on Monday Night Football in Minnesota with Rashad Jennings (thumb) questionable and Shane Vereen (triceps) done for the year.
With Brandin Cooks blanketed all night, Michael Thomas showed how valuable the Saints’ third receiver can be, en route to his third consecutive game with 50 or more yards to open his pro career and will look to replicate that success Sunday against the Chargers.
Torrey Smith's matchup with Dallas' 23rd-ranked pass defense Sunday isn't as enticing as it looks because he'll be defended by top cornerback Morris Claiborne.
Marqise Lee has managed to stay healthy and is averaging six targets, four catches and 47 yards through three games entering a Week 4 matchup against the Indianapolis Colts' 26th-ranked receiving defense.
Blaine Gabbert's ceiling is higher than usual Sunday against a Dallas defense that just got torched for 317 passing yards by Brian Hoyer, but his floor is low as always given his game-manager role for the 49ers.
Blake Bortles' play has been a contributing factor in the Jaguars' 0-3 start, but faces a potentially big day in Week 4 against the Indianapolis Colts, who rank 27th in passing defense.
Wil Lutz knocked through a 57-yarder against the Falcons, looking more comfortable with each successive week and will try to continue that trend Sunday against the Chargers.
Alfred Morris has vultured a couple touchdowns, but Ezekiel Elliott is still the clear go-to running back in Dallas heading into Sunday's plus matchup with the 49ers.
Jeremy Kerley caught seven passes for 61 yards in his last home game, and has a tempting matchup Sunday against a Dallas defense that's allowing 290.0 passing yards per game.
Coming off a low-output week, Julius Thomas has potential in Week 4 against the Indianapolis Colts, who rank 26th in receiving defense.
Devonta Freeman broke the 200-yard barrier in total yards (152 on the ground, 55 as a receiver, plus a touchdown for good measure) but saw three touchdowns swiped by Tevin Coleman on the ground, and he'll look to continue his success Sunday against the Panthers.
Jimmy Graham has the skills to burn the Jets on Sunday, but question marks at quarterback for Seattle put a major dent in his value.
Adam Vinatieri scored just two points in Week 3, but we know by now that the placekicker production is fickle, so you should feel confident in using one of the NFL's all-time great kickers entering Week 4 against the Jacksonville Jaguars.
Sterling Shepard has 233 receiving yards and two scores through three games, but the rookie faces his toughest test yet in Minnesota's ninth-ranked pass defense on Monday Night Football.