Tom Brady has passed for 782 yards and six touchdowns in his first two games back from suspension, and faces a Pittsburgh defense in Week 7 that's allowing 294 passing yards per game, which is 29th in the NFL.
Despite a suspect supporting cast, Andrew Luck is having a nice bounce-back season, limiting interceptions (1.7 INT%) and ranking 15th in QB rating (94.2) entering a Week 7 road game against the Tennessee Titans, who rank 11th in passing defense.
Marcus Mariota has been exceptional in two consecutive weeks and appears to have found a couple of reliable wideout targets -- Kendall Wright and Rishard Matthews -- as the Tennessee Titans prepare for a Week 7 home game against the Indianapolis Colts, who rank 29th in passing defense.
Kirk Cousins might get tight end Jordan Reed (concussion) back Sunday, but is a solid play against Detroit's 23rd-ranked secondary regardless of Reed's status.
Andy Dalton will be up against the Browns in Week 7 after shredding this defense for six combined touchdowns in two 2015 meetings.
Matt Ryan leads the league with more than 2,000 passing yards this season and faces a Chargers secondary in Week 7 that’s allowed four 300-yard passers in six games this season.
Blake Bortles looks to improve his 80.3 quarterback rating (32nd in NFL) in Week 7 against the Oakland Raiders, who rank last in passing defense.
Joe Flacco will take on the Jets this Sunday after throwing just two touchdown passes over his last four matchups.
Sam Bradford likely has a little extra motivation in Week 7 as he faces his former team in the Philadelphia Eagles, who rank fourth against the pass by allowing 207 yards per game but have surrendered five touchdown passes in their last two outings.
Brian Hoyer has topped 300 yards in four straight games and now faces a Packers defense that has allowed at least 286 yards and two touchdowns in three of five outings.
Case Keenum comes into Sunday's London game against the 22nd-ranked Giants secondary hot on the heels of a three-touchdown performance.
Aaron Rodgers faces a Bears defense that is allowing 234 yards per game through the air and seven touchdowns in six weeks, numbers he's only topped twice in five weeks
Coming off his record-breaking 15th career 400-yard game, Drew Brees will hope the Chiefs secondary that shows up on Sunday is the one that gave up five touchdowns to Ben Roethlisberger, and not the one that picked off Ryan Fitzpatrick six times.
Philip Rivers is coming off his worst game of the season, but now gets to face a Falcons defense that's allowed 14 passing TDs through six games.
Tyrod Taylor has four touchdown passes in his last two games, and clashes this Sunday with a Miami Dolphins defense that has allowed nine throwing scores in 2016, which is tied for 17th in the NFL.
Matthew Stafford has at least three touchdown passes in four of six games, but faces a Redskins defense that has not allowed multiple scores through the air since Week 1.
Colin Kaepernick's rushing ability makes him a dangerous option in his second start Sunday against the Buccaneers.
Eli Manning reestablished his connection with Odell Beckham last week, just in time for Sunday's London showdown with the Rams.
Carson Palmer wasn't particularly impressive in his return from a concussion last week, and facing Seattle's fifth-ranked secondary won't make his life any easier Sunday.
Cody Kessler will take on the Bengals Sunday, a defense that has allowed multiple touchdowns to five of the six quarterbacks they’ve faced this season.
Brock Osweiler still hasn't put together 60 minutes of good football, but is hoping to build off an exceptional comeback effort last week when he leads the Houston Texans for a Week 7 matchup against the Denver Broncos, the NFL's top-ranked passing defense.
Jameis Winston’s numbers could be suppressed a bit against the 49ers as the Bucs strive for more balance in their offense (more runs than passes before the bye week) and face a 49ers defense in Week 7 that allowed more than 100 more rushing yards than passing yards to the Bills last week.
Trevor Siemian was remarkably inefficient in Week 6's return from a shoulder injury, and could struggle to move the ball again Monday facing a Texans defense allowing an average QB rating of 80.4, seventh in the league.
Derek Carr had a quiet performance in Week 6, and isn't in a great spot for a rebound Sunday on the road against a Jaguars defense that ranks a surprising eighth in the league in passing yards allowed (218 per game).
Alex Smith attempted a season-low 22 passes in Week 6 as the Chiefs primarily kept the ball on the ground, but he could rebound Sunday against a Saints defense allowing more than 300 passing yards a game.
Ryan Fitzpatrick has been benched for Sunday's tilt with the Baltimore Ravens.
Carson Wentz hasn't topped 250 yards since Week 3, and getting to that mark won't be easy Sunday against Minnesota's sixth-ranked pass defense.
Russell Wilson's limited mobility significantly diminishes his value heading into Sunday's clash with Arizona's third-ranked pass defense.
Blaine Gabbert has lost his job to Colin Kaepernick, and will ride the bench Sunday against Tampa Bay.
Ben Roethlisberger will miss at least Sunday's game against the Patriots as he recovers from knee surgery.
Jay Cutler's return from a thumb injury remains uncertain, as does his role with Brian Hoyer having topped 300 yards in four straight games.
Geno Smith was called upon for mop up duty Monday, and it looks as though he will be the starter Sunday against a Baltimore Ravens defense that has eight interceptions already in 2016.
Landry Jones will have a Sunday matchup against the Patriots that hasn’t given up more than one touchdown pass to any of the last four quarterbacks they’ve faced.
Ryan Tannhill has failed to score a touchdown in two-straight games, and faces a Buffalo Bills defense on Sunday that has allowed a league-low three passing scores in 2016.