Ben Roethlisberger completed 24 or 34 pass attempts for 215 yards, zero touchdowns and two interceptions on Sunday, the first time all season that Roethlisberger threw for zero touchdowns but multiple interceptions, but he has a good match-up in Week 17 in a must-win game against a Cleveland Browns defense that allows 244.2 yards per game through the air but ranks 28th in the NFL with 31 touchdowns allowed through the air.
Tom Brady torched the Miami Dolphins for 356 yards and four touchdowns in their first meeting this season, and New England is still playing for home field advantage throughout the playoffs.
Eli Manning threw for just 234 yards on 29 attempts in the loss to the Redskins, but gets the Eagles and a returning Odell Beckham for the finale.
Matt Ryan looks to build off his big game last week against the Saints secondary that’s allowed the most fantasy points to opposing quarterbacks.
Matthew Stafford has 14 touchdowns and one interception over his last five games and faces a Bears secondary he lit up for a season-high 405 yards to go with four touchdowns in an October 18 meeting.
Ryan Fitzpatrick has 13 touchdowns as compared to just one interception over his last five games for the streaking Jets, but faces his former team, the Buffalo Bills, against whom he struggled in the first meeting between the two squads.
Palmer (265 yards passing, 2 TDs) could have had a bigger game but failed to do much damage in the second half before the game got out of hand and Arizona pulled the plug on most of its starters but look for a full workload in a Week 17 home game against Seattle with home field advantage throughout the playoffs still in play for Arizona.
Drew Brees was excellent against the Falcons in the teams’ first meeting, completing more than 75 percent of his passes for more than 300 yards, one of just two quarterbacks to achieve that feat.
Blake Bortles has tossed 13 touchdown passes (three interceptions) in the last four games as the Jacksonville Jaguars prepare for their Week 17 road game against the Houston Texans, who rank 15th in passing touchdowns allowed (24).
.J. McCarron completed 22 of 35 passes for 200 yards and a touchdown, and also rushed four times for 21 yards but lost a fumble on Monday night against the Denver Broncos, and though he has a sprained left wrist he currently plans to play in Week 17 against a Baltimore Ravens pass defense that has allowed 239 yards per game (17th in NFL) and is tied for 20th with 28 touchdown passes allowed.
The Tennessee Titans have not committed either way about the status of Marcus Mariota (knee) for Week 17 against the Indianapolis Colts, but the prudent move is to make him inactive and have Zach Mettenberger start.
Jay Cutler faces a Lions defense that has given up at least two touchdown passes in seven of their last nine games, but Cutler's potential could be tied to wide receiver Alshon Jeffery's hamstring injury more than the matchup.
Sam Bradford threw for a season-high 380 yards on 56 attempts in the loss to Washington, giving him 741 yards on 97 attempts the past two weeks.
Kirk Cousins threw for 365 yards and four scores against Philadelphia, giving him eight touchdowns the past two weeks, but could see limited action against Dallas with the division wrapped up.
Cam Newton will look for the cap on his magnificent, MVP-caliber season against the Bucs, whom he struggled against last time out.
Teddy Bridgewater had his eighth game with less than 200 yards passing last week, but he could be called upon to throw more if the Vikings fall behind and you know he'll play a full four quarters with the division on the line against a Packers team which he threw for 296 yards against in Week 11.
Wilson threw for less than three touchdowns for the first time since Week 10 but did salvage his day with his second TD pass of the game in the last minute but will face his toughest test in a while on the road in Arizona in Week 17.
Aaron Rodgers faces a Vikings defense that has allowed at least two touchdown passes in four straight games and six of their last seven outings.
Brock Osweiler threw for at least 290 yards for the third straight game in Week 16's win over the Bengals, and faces a soft Chargers defense Sunday as the Broncos attempt to clinch the AFC West and a first round bye.
Brian Hoyer remaied in the NFL concussion protocol early in the practice week for Week 17 against the Jacksonville Jaguars, but head coach Bill O'Brien said he will start if medically cleared.
Tyrod Taylor did not find the end zone in Sunday's win over the Dallas Cowboys, and had just one touchdown against the New York Jets in the first clash between the two teams.
Derek Carr failed to throw multiple touchdowns last week for the first time in five games, and has a tough road matchup Sunday against a Chiefs defense that's second in the league in QR rating against (75.9).
Philip Rivers had a fairly quiet performance in Week 16's loss to the Raiders, and faces a Broncos defense Sunday that leads the league in QB rating against (78.3).
Jameis Winston has made huge strides since his four interception outing in his first meeting with the Panthers, but their voracious defense will continue to terrorize him.
Ryan Tannehill is banged up, has not throw a touchdown pass in each of the last two games, and also did not toss a touchdown against the New England Patriots in the first meeting between the two squads.
Brandon Weeden has been effective while filling in for Brian Hoyer (concussion), but head coach Bill O'Brien said if Hoyer is medically cleared, he will start Week 17 against the Jacksonville Jaguars.
Marcus Mariota missed Week 16 with a knee injury, but has not been ruled out of the Tennessee Titans' Week 17 game against the Indianapolis Colts, though the prudent move would be to sit him out.
Johnny Manziel completed 13 of 32 passes for 136 yards and an interception but added 11 carries for 108 yards on Sunday against the Kansas City Chiefs, but he is currently in the concussion protocol and questionable to play in Week 17 against a Pittsburgh Steelers defense that is solid against the run but allows 278.2 passing yards allowed/game, 30th in NFL.
Alex Smith hasn't thrown for over 200 yards in four straight games, but faces a Raiders defense Sunday that's allowed 266 passing yards a game, 27th in the league.
Stephen Morris, a member of the Indianapolis Colts for less than two weeks, is the healthiest quarterback on the roster as the Colts enter a Week 17 game against the Tennessee Titans with a faint hope of making the postseason.
Keenum fared about as well as could be expected (14-of-23, 103 yards passing and a TD) in a hostile environment in Seattle in Week 16 and should have an easier time against the 49ers in Week 17 but the majority of the offense still flows through running back Todd Gurley and the ground game.
Ryan Mallet completed 28 of 41 passes for 274 yards and a touchdown in his debut with the Baltimore Ravens against the Pittsburgh Steelers in Week 16, and next up has a match-up against a Cincinnati Bengals pass defense that has allowed 246.3 yards per game (20th in NFL) but only 17 touchdown passes (tied for third in the NFL).
Gabbert (225 yards passing, two touchdowns) threw for multiple scores for the first time since Week 9 and a Week 17 matchup against a Rams defense that has played better of late figures to test the struggling San Francisco offense.
Josh Freeman was signed this week as the Indianapolis Colts have been hit by injuries at quarterback entering a Week 17 game against the Tennessee Titans.
B.J. Daniels was used for 15 snaps last week, mostly doing the read option, and will continue in a non-traditional role as the Houston Texans host the Jacksonville Jaguars in Week 17.
Peyton Manning is nearly recovered from his foot injury, but will still back up Brock Osweiler on Sunday against the Chargers as the Broncos try to clinch the AFC West.
Matt Hasselbeck (neck, rib, shoulder) is considered doubtful to play in the Indianapolis Colts' Week 17 game against the Tennessee Titans.
Kellen Moore completed just 13 passes for 186 yards in his first NFL start in the loss to Buffalo.
Ryan Lindley and Josh Freeman were signed this week, which gives you an indication of the state of the Indianapolis Colts' quarterback position entering a Week 17 game against the Tennessee Titans.
Will the Indianapolis Colts gamble using Andrew Luck (kidney) with their faint playoff hopes alive in their Week 17 game against the Tennessee Titans?