Rawls racked up just 81 yards on 21 carries but managed a score in his first week since being anointed the starter for the injured Marshawn Lynch and should continue to see a heavy workload against the Vikings in Week 13.
Darren McFadden ran for just 11 yards on 10 carries, though he did add 45 receiving yards, against Carolina and should fare a good bit better against a poor Washington run defense.
Chris Ivory got back into the scoring column Sunday and faces a New York Giants defense that has been mediocre against the run in 2015.
LeGarrette Blount was barely used in Sunday's loss, though that could change against a Philadelphia Eagles defense allowing 126.6 yards per game on the ground.
LeSean McCoy has scored in three of the last four games, but faces a Houston Texans defense that has allowed just two total touchdowns over the last four contests.
Jeremy Hill rushed for 86 yards on Sunday against the St. Louis Rams in his best yardage output of the season, but he did leave early with an ankle injury, and if he can play through it in Week 13 he will face a poor Cleveland Browns run defense (32nd in the NFL in rushing yards allowed per game) that nevertheless held him to only 52 yards on 15 carries in their last meeting back in Week 8.
Giovani Bernard totaled 67 yards on 12 touches on Sunday against the St. Louis Rams, very similar in production to the 86 yards on 14 carries that he produced the last time he faced his Week 13 opponents, the Cleveland Browns.
Gurley found little room to run against the Bengals, finishing with just 19 yards on nine carries, and has just 130 yards rushing over the last three weeks as team's simply stack against the run given the Rams passing attack and figures to have another tough game against the Cardinals in Week 13 despite his obvious talent.
Johnson could be looking at a big uptick if the injuries to Chris Johnson and Andre Ellington land Johnson the starting role but may get off to a sluggish start against a Rams defense that has allowed just six rushing scores to date this season.
Draughn continues to dominate the touches out of the San Francisco backfield (15 carries, five catches in Week 12) and figures to continue doing so until Carlos Hyde returns and could make for a sneaky option against a Bears defense that is allowing the fourth-most rushing yards per game (128.5) this season in Week 13.
Matt Jones showed his big-play ability on a 45-yard reception but was otherwise held in check in the win over New York with just eight carries for 19 yards on the ground.
Brandon Bolden hauled in a touchdown pass Sunday, but remains in competition for touches out of the backfield with James White and LeGarrette Blount, leaving some mystery as to how the work will be divided.
Taylor looks to have an expanded role in Week 13 with Chris Johnson and Andre Ellington both dealing with injuries but figures to yield most of the work to rookie David Johnson in a revamped Arizona backfield as they take on the Rams in Week 13.
DeMarco Murray had just 30 yards on 14 carries and was held without a catch for the first time this season in the loss to Detroit, and has just one 100+ rushing yard effort this season.
Alfred Morris ran the ball 23 times for 78 yards despite some uncertainty about his availability for the game, but still has yet to find the end zone this season.
Ellington was looking at a larger share of the carries with the leg injury to Chris Johnson but a case of turf toe throws his availability for Week 13 against the Rams into question.
Lamar Miller has just 89 rushing yards and zero touchdowns over his last three games, and the Baltimore Ravens have a top-10 defense against the run.
Shane Vereen's 15 yards rushing led the team in a loss to Washington but he was held to under 30 yards receiving for the fifth time in the past six games.
Kenjon Barber picked up seven carries for 30 yards in the loss to Detroit and could see limited carries again against New England if Ryan Mathews remains sidelined.
Ryan Mathews was held out of the Thanksgiving contest due to a concussion, and would get a tough assignment against New England this week if he's able to return.
Orleans Darkwa had just two carries against Washington, continuing the trend as one quarter of the least productive running back committees in recent memory.
Darren Sproles had just 25 total yards in the loss to Detroit despite the absence of Ryan Mathews for the second straight game.
Robert Turbin picked up just two carries against Carolina, but showed good burst in his debut the week prior and figures to see more action this week against a poor Washington run defense.
Jay Ajayi had seven touches in his last game, but remains firmly behind Lamar Miller on the depth chart.
Karlos Williams may not be available against the surging Houston Texans due to a shoulder injury.
Rashad Jennings had just six carries for 14 yards in what continues to be the least productive running back committee in recent memory.
Bilal Powell has received at least eight touches in two-straight games, but remains firmly behind Chris Ivory on the depth chart.
Jackson saw limited action (one carry, two targets) behind running back Thomas Rawls and doesn't figure to see any additional work as long as Rawls is healthy as Seattle travels to Minnesota in Week 13.
Cunningham isn't a threat to take away any looks from Todd Gurley and will thus need to make the most of a very limited number of touches for the Rams against the Cardinals in Week 13.
Johnson had a hugely disappointing (12 carries, 17 yards) effort in Week 12 before leaving with a leg injury that clouds his availability for Week 13 and possibly beyond.
Mason caught a team-high seven balls out of the Rams backfield and could see a similar workload in Week 13 if the Rams get behind early against the Cardinals.
Lynch continues to be sidelined following surgery to repair a sports hernia as Seattle travels to Minnesota in Week 12.
James White had five touches for just six yards Sunday night, and it remains to be seen how coach Bill Belichick will use his running backs on a week-to-week basis.
Andre Williams had just two carries and one yard in the loss to Washington, giving him just 59 rushing yards the past seven weeks.