Baldwin continues to hold some value in PPR formats by leading the Seattle passing attack but will need to shake off a low-ankle sprain as Seattle hosts the Steelers in Week 12.
Cecil Shorts is healthy again after missing a couple of games with a hamstring injury and Week 12 could be a good one for the Houston Texans' receivers against the New Orleans Saints, who rank 30th in pass defense (290.5 ypg).
Donte Moncrief, who's scored a team-high five touchdowns in 2015, looks to snap a three-week scoreless drought in Week 12 when the Indianapolis Colts host the Tampa Bay Buccaneers, who are 30th with 21 passing touchdowns allowed.
Kamar Aiken led the Baltimore Ravens in receptions, targets, and scored the only touchdown on Tuesday but will have to establish chemistry with new quarterback Matt Schaub this week against a Cleveland Browns defense that is 26th in the NFL in passing yards allowed and 30th in passing touchdowns allowed.
Kendall Wright, who has missed the Tennessee Titans' previous three straight due to a knee injury, is expected to play in Week 12 against the 30th-ranked passing defense, the Oakland Raiders, who give up 290.5 passing yards per week.
Marquess Wilson could function as the team's second receiver Thursday against the Packers with Eddie Royal and tight end Martellus Bennett both dealing with injuries, giving him a chance to build on last week's 102 yard performance.
Sammy Watkins has six catches for just 53 yards over his last two games, but faces a Kansas City passing defense that is in the middle of the pack in terms of passing yards and touchdowns surrendered this season.
Javorius Allen has taken over the running back responsibilities for the Baltimore Ravens with Justin Forsett done for the season, and this week he has an excellent match-up against a Cleveland Browns defense that is dead last in the NFL with 138.8 rushing yards allowed per game.
Terrance Williams re-emerged to a state of fantasy relevance with the return of Tony Romo with a team-high 79 yards on four catches in the win over Miami.
Duke Johnson continues to be out-carried by Isaiah Crowell but his receiving ability allows him to be the more effective back for the Cleveland Browns, and while Week 12 opponent the Baltimore Ravens is solid against the run (97 yards, 0.6 rushing touchdowns per game) they are weaker in pass defense (24th in the NFL with 257 passing yards allowed per game), which is Johnson's specialty.
J.J. Nelson parlayed a hamstring injury to wideout Michael Floyd into an increased role in Week 11 and will look to build off that effort (four catches, 142 yards and a touchdown) if Floyd is unavailable again in Week 12 against San Francisco.
Jeremy Hill had a huge bounce-back effort in Week 12 with 45 rushing yards and two touchdowns, but this week faces a tough test in a St. Louis Rams defense that allows 108.1 yards per game on the ground but has only allowed six rushing touchdowns all season.
Floyd was absent in Week 11 due to a hamstring injury but will look to restart his four-game TD streak if he can get back into the lineup in Week 12 against San Francisco.
Ronnie Hillman is coming off his third 100-yard rushing game of the season, but isn't likely to have as much success Sunday against the Patriots defense that's allowed just 88.8 rushing yards a game, second in the league.
With three touchdowns the last two weeks, Ahmad Bradshaw is getting more involved in the offense and that should continue in Week 12 when the Indianapolis Colts host the Tampa Bay Buccaneers, who rank 13th in overall defense (339.1 total ypg).
Jonathan Stewart has been incredibly steady all season, but the Cowboys have allowed only one 100-yard rusher, despite allowing the fourth most fantasy points to opposing running backs.
Vincent Jackson made his triumphant return and should be a good play against the Colts forgiving secondary.
Nate Washington has just four catches for 45 yards the last two weeks, but his fortunes could change in Week 12 when the Houston Texans face the league's 30th-ranked pass defense in the New Orleans Saints.
Charles Sims’ usage will prevent him from being a top fantasy option, but his pass catching ability should help him against the sub-par Colts defense.
The veteran Tim Hightower saw a team-high 11 carries thanks to the blowout but likely won’t factor too much into the fantasy mix with a healthy and rested Ingram.
Johnson's primary value comes from his use on special teams but he's slowly emerging as a receiving threat out of the backfield and will look to continue that trend against the 49ers in Week 12.
Chris Givens has been targeted 14 times in the past two weeks but only converted six to receptions, and now will have to establish chemistry with new quarterback Matt Schaub, though he does have a good matchup this Monday against a Cleveland Browns pass defense that is 26th in the NFL with 268.5 yards allowed per game and tied for 30th with 21 passing touchdowns allowed.
Quietly, Jerricho Cotchery has established himself as a dependable option of the outside for Cam Newton and the undefeated Panthers, pulling in four receptions for 57 yards last week.
Josh Huff hauled in his third touchdown of the season against Tampa Bay, though he was targeted just one time after 21 targets the prior five games.
Leonard Hankerson has found himself as the Falcons’ second option on the outside, but will go against a tough Vikings secondary.
Tennessee Titans interim head coach Mike Mularkey has made it a point to give Dorial Green-Beckham more playing time (84 percent of offensive snaps last week) and that will continue in Week 12 when the Titans face the Oakland Raiders, who rank 30th in passing defense (290.5 ypg).
Chris Hogan was the leading receiver for the Bills on Monday, and will clash with a Kansas City Chiefs defense that has been mediocre against the pass in 2015.
Karlos Williams did not find the end zone in a game for the first time in his career Monday against New England, and faces a Kansas City Chiefs defense that has allowed just five rushing touchdowns in 2015, which is tied for sixth in the NFL.
Just six touches and 26 yards for Shane Vereen in the loss to New England after two straight games of 10 touches.
With Kendall Wright (knee) expected to return, Harry Douglas' opportunities will diminish in Week 12 when the Tennessee Titans host the Oakland Raiders, who rank 30th in pass defense (290.5 ypg) and 27th in scoring defense (25.9 ppg).
Lockett made the most of his limited work with a pair of touchdowns in Week 11 and will have to find a way to do so again in Week 12 against the Steelers with most of the offense flowing through Thomas Rawls, Doug Baldwin and Jimmy Graham.
Chris Harper could see some action due to the injuries to Julian Edelman, Danny Amendola and Aaron Dobson.
Tevin Coleman had just 2.8 yards per carry last week and—if Devonta Freeman can’t go—will be the bell cow against the Vikings highly touted front.
Draughn figures to continue shouldering the load in the San Francisco ground game for as long as Carlos Hyde remains sidelined but a Week 12 matchup against the Cardinals figures to limit Draughn's upside.
Marques Colston has been relegated down the depth chart and has more than 50 receiving yards just twice in nine games this season.
Brown wasn't targeted in a Week 11 win despite wideout Michael Floyd being sidelined with a hamstring injury and may have lost some looks going forward to J.J. Nelson as the team prepares for a Week 12 matchup against the 49ers.
Cole Beasley had just one catch in Tony Romo's return, though he did narrowly miss a fourth-quarter touchdown.
Fourteen of Griff Whalen's 18 targets have come in the last three games heading into the Indianapolis Colts' Week 12 game against the Tampa Bay Buccaneers, who rank 13th in passing defense (234.6 ypg).
Bilal Powell proved an extremely capable receiver out of the backfield in New York's last contest, hauling in five passes for 67 yards, and looks to be fully healed from an ankle injury suffered earlier in 2015.
Orleans Darkwa's five carries trailed only Rashad Jennings in the loss to New England but has just 103 yards on 23 carries teh past four games as the committee approach continues.
Jonathan Grimes was part of the Houston Texans' version of the Wildcat offense unveiled in Week 11 and he looks to capitalize on the success he had in Week 12 when they play the New Orleans Saints, who rank last in overall defense (424.3 total ypg).
Rashad Greene returned from a thumb injury in Week 11 and looks to make an impact as a return man in Week 12 when the Jacksonville Jaguars host the San Diego Chargers, who rank 26th in punt return average (10.3 ypr) and 31st in kickoff returns (28.7).
David Cobb, who is back from a calf injury that forced him to miss the Tennessee Titans' first nine games, will get increased snaps in Week 12 against the Oakland Raiders, but is not yet ready for a big role and will continue to back up Antonio Andrews.
Thanks to Devin Funchess’ improvement, Ted Ginn Jr. can slide into the role of grabbing underneath routes he’s more comfortable in against a Cowboys secondary that’s not particularly forgiving.
Dwayne Harris's nine targets trailed only Odell Beckham's 12 in a loss to the Patriots, but he's still remains inconsistent in his involvement and makes for a tough start now that the bye weeks have passed.
Chris Thompson had just 17 total yards in the loss to Carolina but could be looking at an uptick in usage with the injury to Alfred Morris and the continued fumbling problems from Matt Jones.
James White scored two touchdowns Monday against the Bills, but had just four touches in all and faces a Denver Broncos defense allowing the fewest yards in the NFL.
Matt Jones' continued ball security issues had him on the sidelines for the bulk of the Carolina game, though the injury to Alfred Morris could open the door again.
Isaiah Croweell had negative one total yards on seven touches in Week 10 against the Pittsburgh Steelers, but will try to bounce back in Week 12 against a Baltimore Ravens run defense that allows 97 yards per game on the ground.
Robert Woods was targeted nine times against the New England Patriots, and will face a Kansas City Chiefs defense allowing 234 passing yards per game this season.