Terrelle Pryor will face Washington on Sunday, and it’s possible that he’ll continue to see snaps as a Wildcat quarterback, which could give him major upside this week.
Josh Lambo connected on three field goals in Week 3 and gets a very favorable matchup Sunday at home against a Saints defense that's allowed 32.0 points per game so far, second-worst in the league.
Jamison Crowder already has 16 catches for 175 yards and two touchdowns this season, and likely won't slow down Sunday against a Browns team allowing 294.3 passing yards per game.
Jordan Howard has an inviting matchup against a Lions defense which is allowing a league-high 5.1 yards per carry, and would see a boost in his appeal should Jeremy Langford (ankle) miss the contest.
Kyle Rudolph has seen eight targets or more in all three games this season, catching two touchdowns, but faces a Giants defense Monday night that has yet to allow a tight end to reach the end zone.
Isaiah Crowell has a Sunday contest against a Washington defense that has allowed six touchdowns to running backs through three games this season.
Joe Flacco will be at home to take on a Raiders’ defense that he had 384 passing yards and two touchdowns against when facing them in 2015.
Dak Prescott has scored on the ground in back-to-back games, which makes him a solid Week 4 option against a 49ers team that has struggled to contain dual-threat quarterbacks.
Cole Beasley doesn't make many big plays, but rookie quarterback Dak Prescott should continue to look for him early and often Sunday against the 49ers after completing 20 passes for 213 yards to him through three weeks.
Dennis Pitta will face a Raiders’ defense on Sunday that has allowed at least 59 receiving yards to three different tight ends this season.
Pierre Garcon has been outplayed by both DeSean Jackson and Jamison Crowder among Redskins wide receivers, but could still put up big numbers Sunday against Cleveland's 25th-ranked pass defense.
Mike Wallace have a Sunday contest against the Raiders who have allowed three different wide receivers to post at least 106 yards and a touchdown against them in 2016.
Fozzy Whittaker will look for more than five carries as he’s just a week removed from his 100-yard performance against the 49ers for Sunday’s divisional matchup against the Falcons, who allowed the sixth-most fantasy points to opposing running backs in 2015.
Vance McDonald (hip) is a solid play if he suits up Sunday against Dallas' 23rd-ranked pass defense.
Cameron Brate caught two touchdowns last week and may be key in unlocking Denver’s tough defense, as they allowed the 11th-most fantasy points to opposing tight ends last season.
Jacob Tamme saw his production dip after 11 receptions for 126 yards in the first two weeks, but faces a Panthers' defense that’s allowed 145 yards and two scores to the opponent's featured tight end over the past two weeks.
Cairo Santos remains perfect on the season and should have a productive game Sunday against a Steelers defense that ranks in the middle of the pack with 22.0 points allowed per game in 2016.
Dan Carpenter kicked two field goals and three extra points last weekend, though will face a New England defense on Sunday that allows just 15 points per game.
Charles Sims will be a strong play for the Bucs on Sunday against the Broncos after they allowed 143 yards and 4.9 yards per carry to the Bengals last weekend.
Dwayne Washington is the best bet for Detroit in a limited rushing offense, and faces a Bears defense that ranks second-to-last against the run, allowing 142.7 yards per game
Orlean Darkwa could play a major role on Monday Night Football in Minnesota with Rashad Jennings (thumb) questionable and Shane Vereen (triceps) done for the year.
With Brandin Cooks blanketed all night, Michael Thomas showed how valuable the Saints’ third receiver can be, en route to his third consecutive game with 50 or more yards to open his pro career and will look to replicate that success Sunday against the Chargers.
Marqise Lee has managed to stay healthy and is averaging six targets, four catches and 47 yards through three games entering a Week 4 matchup against the Indianapolis Colts' 26th-ranked receiving defense.
Blaine Gabbert's ceiling is higher than usual Sunday against a Dallas defense that just got torched for 317 passing yards by Brian Hoyer, but his floor is low as always given his game-manager role for the 49ers.
Wil Lutz knocked through a 57-yarder against the Falcons, looking more comfortable with each successive week and will try to continue that trend Sunday against the Chargers.
Alfred Morris has vultured a couple of touchdowns, but Ezekiel Elliott is still the clear go-to running back in Dallas heading into Sunday's favorable matchup with the 49ers.
Jeremy Kerley caught seven passes for 61 yards in his last home game, and has a tempting matchup Sunday against a Dallas defense that's allowing 290.0 passing yards per game.
Adam Vinatieri scored just two points in Week 3, but we know by now that the placekicker production is fickle, so you should feel confident in using one of the NFL's all-time great kickers entering Week 4 against the Jacksonville Jaguars.
Can Will Fuller and the Texans make the necessary adjustments this week after the rookie was held to 31 yards in Week 3? They face a familiar team in the Tennessee Titans, who rank 11th in receiving defense.
Jerick McKinnon out-touched Matt Asiata 17 to seven in the team's first game without Adrian Peterson, but faces a stern test Monday night against the Giants' fifth-ranked rush defense that is allowing only 77.3 yards per game.
Victor Cruz has put up at least 70 receiving yards or a touchdown in every game this season, but Minnesota's ninth-ranked defense won't make extending that streak easy Monday night.
Trevone Boykin threw a touchdown last week, and could be called into action Sunday against the Jets' 21st-ranked pass defense if Russell Wilson is unable to play through a sprained MCL.
Jack Doyle has been unable to repeat his season-opening, two-TD performance in Week 1, but is tied for second on the team in targets and is second in receptions entering a Week 4 matchup against the Jacksonville Jaguars.
Garrett Celek could monopolize the receiving production at the tight end position Sunday against the Cowboys if Vance McDonald (hip) is unable to suit up.
Duke Johnson will face Washington on Sunday where he’ll look to have a fourth straight game with at least 50 total yards.
Jay Cutler would have an inviting matchup against a Lions defense that has allowed a league-high 10 touchdown passes should he be able to return to action after missing Week 3 due to a thumb injury.
Phil Dawson missed one of two tries last week, but will look to rebound in a home matchup with Dallas's 22nd-ranked defense Sunday.
Theo Riddick managed only nine yards on 10 carries last week heading into a matchup against a Bears defense that ranks 31st against the run, allowing 142.7 yards per game.
Trevor Siemian had the best game of his young career last week in Cincinnati, and could be in line for another strong performance Sunday against a Buccaneers defense that ranks 29th in QB rating allowed at 106.4.
Continuing his trend of only kicking short field goals, Matt Bryant extended his streak to 6-for-6 on field goals (all within 34 yards) this season, and he gets to kick in the friendly confines of the Georgia Dome on Sunday against the Panthers.
Nick Novak was shut out last week after averaging 12 points per game the first two weeks. Look for him to get back on the scoring train Week 4 against the Tennessee Titans.
Cameron Artis-Payne averaged 3.9 yards per carry against the Vikings and should find more room to run Sunday against the Falcons, who allowed the sixth-most fantasy points per game to opposing running backs last season.
Jesse James will line up against the Chiefs this Sunday night to face a defense that’s yet to allow more than 20 receiving yards to an opposing tight end this season.
Cody Parkey will face Washington on Sunday after connecting on just three of six field goal attempts last week.
Marcedes Lewis has been a nuisance to top receiving tight end Julius Thomas, stealing targets and scoring a touchdown, but is the clear second option at the position entering a Week 4 meeting with the Indianapolis Colts, who rank 20th in yards allowed to tight ends.
Sammie Coates will be up against the Chiefs in Week 4 after posting at least 50 receiving yards in each games he’s played this year.
Ryan Griffin got some extra looks last week following an injury to Stephen Anderson, but the injury is not considered serious and Griffin could be back to seeing minor targets in the Texans' Week 4 game against the Tennessee Titans.
Hunter Henry caught five passes for 76 yards in his first NFL start in Week 3, and could get another Sunday against the Saints if Antonio Gates' hamstring sidelines him once again.
Derrick Henry is getting more and more playing time but remains the second back behind DeMarco Murray in Tennessee's run-first offense. He could vulture a red-zone touchdown in Week 4 against the Houston Texans.
Josh Doctson was scratched with an Achilles injury last week, and questions about his health make him an unreliable option in what would otherwise be a great Week 4 matchup with the Browns.