Just 38 yards on five catches, but 12 more targets, and gets to square off a yielding 49ers' defense.
Keenan Allen is on pace for a career season through four games, and as the only healthy Chargers receiver he should see a high target volume Sunday against a vulnerable Steelers secondary.
Julio Jones may have fallen way off his season-long pace last week (4-38-0), but that doesn't mean he's not still the best receiver in football and should show that Sunday against the Redskins.
Leonard Hankerson, now the No. 2 receiver on the high-octane Falcons offense, should have another good week against the Redskins after his first 100-yard receiving day since 2011.
Matthews has been quiet the past two weeks, but he's easily the safest part of Philadelphia's shaky offense, and he'll face a porous New Orleans secondary in Week 5.
Demaryius Thomas continues to a high target volume and has a favorable matchup in Week 5 against a Raiders defense he hit up for two 100-yard games last year and which is allowing over 300 passing yards a game this season.
Averaging 10 catches on 14 targets through three games, Edelman should be in for another heavy dose of looks against a Cowboys defense that has allowed 307.5 yards per game in their last two outings.
Fitzgerald should have no problem continuing his hot start to the season in a Week 5 matchup against a Lions defense that is yielding 271.5 passing yards per game.
Cobb's volume remains high, averaging 10 targets over the past three games, but faces a sound Rams defense in Week 5 that has allowed only one touchdown to a wide receiver all season.
Could benefit from the injury to tight end Jordan Reed on an offense that has thrown the ball 94 times the past two weeks.
Jeremy Maclin had another huge game in last week's loss to the Bengals when Alex Smith wad forced to play catch-up, but he should see a lower target volume Sunday as the Chiefs lean heavily on Jamaal Charles to attack a vulnerable Bears run defense.
Emmanuel Sanders should be able to rebound from a quiet Week 4 against a Raiders defense Sunday that's allowing more than 300 passing yards a game, and which surrendered 11 catches for 140 yards and two TDs to Sanders in two games last season.
Baldwin gets a favorable draw against a Bengals defense that has allowed the sixth-most passing yards per game (279.0) through the first four weeks of the season in a Week 5.
With so many of his teammates hobbled by injuries, Harvin could see some extra targets against a shaky Tennessee secondary.
Scored for the second straight week and spends another week as WR2 with the injury setback to Victor Cruz.
Donte Moncrief leads the Indianapolis Colts in touchdowns as the prepare for a Week 5 game against the Houston Texans.
Brown will continue to have to fight for targets in the Arizona passing attack but a Week 5 matchup against the Detroit Loins should give him chances to make an impact.
Allen Hurns has been a more consistent receiver in his second season with the Jacksonville Jaguars and he'll remain the number two target in Week 5 against the Tampa Bay Buccaneers.
With 18 targets the past two weeks, Crowder makes for a sneaky play with a good matchup if DeSean Jackson remains sidelined this week.
Allen Robinson leads the NFL with 22 receiving yards per catch entering a Week 5 matchup against the Tampa Bay Buccaneers.
Mike Evans was out-targeted by Vincent Jackson 15-to-8 and will hope to get on the right side of that balance against the middle-of-the-pack Jaguars secondary.
Should Jeffery return from a hamstring injury, he'll face a Chiefs defense that has eight opposing receivers top 80 yards in four games while allowing 11 touchdowns.
Royal's upside will tie directly to the availability of Alshon Jeffery, but facing a Chiefs defense that allows 296 yards and 31.3 points per game, there should be enough to go around for Royal.
DeAndre Hopkins has posted two straight 100-yard receiving games as the Houston Texans prepare for a Week 5 game against the Indianapolis Colts, the 23rd-ranked defense in passing yards allowed per game.
Kendall Wright has benefited form better quarterback play this season and will face the league's 29th-ranked passing defense in Week 5 when the Buffalo Bills visit Nashville.
Brandin Cooks will look to convert more of his targets into receptions (4-of-8) as the Saints take on the Eagles' poor secondary (284.8 receiving yards per game) on Sunday.
Vincent Jackson will look to build off his huge week (10-147-1) in Sunday's matchup against the middling Jaguars.
Nate Washington is day-to-day with a hamstring injury leading up to Week 5, a Thursday night game against the Indianapolis Colts.
Marques Colston will look to get more than the fifth-most targets on the team in Sunday's matchup against the poor Eagles secondary.
Boldin might have his best chance at turning around a disappointing start with a Week 5 game matchup against the Giants' league-worst (316.3 yards per game) pass defense.
Roddy White had his best game in weeks (2-8-0), but that would still net less than one fantasy point in non-PPR leagues.
Tate could draw extra looks against the Cardinals should Patrick Peterson shadow Calvin Johnson, but it's a defense that is allowing only 199 yards per game, giving Tate minimal upside.
Marqise Lee is dealing with a hamstring injury that leaves him questionable entering a Week 5 matchup against the Tampa Bay Buccaneers.
Andre Johnson has just three targets the past two weeks, but has a motivational game in Week 5 when the Indianapolis Colts take on his former team, the Houston Texans.
Watkins may miss a second straight game with a calf strain, but he'll face a shaky defense if he's able to play.
Amari Cooper is on pace for a truly impressive rookie season, but has a tough matchup Sunday against a Broncos defense that has allowed just two total receiving TDs and 185 passing yards per game this season.
Mumphrey will take on a larger role as Cecil Shorts (shoulder) has been ruled out for the Houston Texans' Week 5 home game against the Indianapolis Colts.
Kearse hasn't found the end zone but has topped 75 yards receiving in three of his four games this year as Seattle takes on a Bengals defense that is allowing the sixth-most passing yards per game (279.0) in the league so far.
Austin may have a tough time repeating his Week 4 performance (six catches, 96 yards and two scores) against a Packers defense that has yielded just four passing touchdowns and under 200 yards passing per game this season.
Dorial Green-Beckham is on a roll, having caught touchdown passes in two straight games and looking to make it a third straight in Week 5 when the Tennessee Titans host the Buffalo Bills.
Johnson's volume and potential for a score keep his value from bottoming out, but against a Cardinals secondary led by corner Patrick Peterson that is allowing only 199 yards per game through the air, expectations can be kept in check.
The New Orleans defense provides favorable matchups for pretty much every offensive position, but Agholor is averaging just four targets per game.
Going up against the league's 28th ranked pass defense offers Wilson a chance to replicate last week's career-high 80 yard performance, but he would see a decrease in targets should Alshon Jeffery return from a hamstring injury.
Smtih and the San Francisco passing attack will look to take advantage of a New York Giants pass defense that has allowed a league-high 316.3 passing yards per game in Week 5.
Darrius Heyward-Bey has been outplaying Markus Wheaton for the second wide receiver slot, but both may take a backseat to the recently-returned-from-suspension Martavis Bryant as soon as this week against a San Diego Chargers team that is tenth in the NFL with 225 passing yards allowed per game.
Harry Douglas is averaging just 3.3 yards per target in the Tennessee Titans' high-volume offense as he enters a Week 5 game against the Buffalo Bills, who have given up the third most touchdowns to wideouts this year.
Coming off of his first touchdown since October 16, 2014, Amendola remains fourth at best in the pecking order for targets from Tom Brady, making him hard to trust even against a Cowboys secondary that has allowed 307.5 yards per game in their last two contests.
Coming off of his first game of the year without a touchdown, Jones faces a Rams secondary that has allowed only three receiving touchdowns all season, with just one going to a wideout.
Michael Crabtree could see more targets than usual Sunday as Derek Carr unloads the ball quickly against the league-leading Broncos pass rush, but it's unlikely to result in a spike in Crabtree's production.
T.Y. Hilton's knee injury is no longer a bother entering Week 5 against the Houston Texans.